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Merck
CN

1.07428

4-羟基苯甲酸丙酯钠盐

EMPROVE® ESSENTIAL, Ph. Eur., BP, NF

别名:

Propyl 4-hydroxybenzoate sodium salt, 4-Hydroxybenzoic acid propyl ester sodium salt, Propylparaben sodium salt

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关于此项目

经验公式(希尔记法):
C10H11NaO3
化学文摘社编号:
分子量:
202.18
UNSPSC Code:
12352108
EC Index Number:
252-488-1
MDL number:
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产品名称

4-羟基苯甲酸丙酯钠盐, EMPROVE® ESSENTIAL, Ph. Eur., BP, NF

SMILES string

[Na+].[O-]c1ccc(cc1)C(=O)OCCC

InChI

1S/C10H12O3.Na/c1-2-7-13-10(12)8-3-5-9(11)6-4-8;/h3-6,11H,2,7H2,1H3;/q;+1/p-1

InChI key

IXMINYBUNCWGER-UHFFFAOYSA-M

agency

BP
NF
Ph. Eur.

product line

EMPROVE® ESSENTIAL

form

solid

pH

9.5-10.5 (20 °C, 1 g/L in H2O)

mp

302 °C

density

1.24 g/cm3 at 25 °C

application(s)

liquid formulation
ophthalmics
pharmaceutical
semi-solid formulation
solid formulation

storage temp.

15-25°C

Quality Level

Application

Propyl 4-hydroxybenzoate has antimicrobial characteristics and is used as preservative in pharmaceutical formulations and cosmetics. It can be combined with other parabens like methyl 4-hydroxybenzoate or ethyl 4-hydroxybenzoate. The sodium salt provides improved solubility in water compared to standard propyl 4-hydroxybenzoate.

Disclaimer

The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Corrosion

signalword

Danger

hcodes

Hazard Classifications

Eye Dam. 1

存储类别

11 - Combustible Solids

wgk

WGK 3


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Find key considerations for the selection and use of preservatives in a range of different therapeutic applications including topical, oral, transmucosal, inhalation, and otic, as well as injectables.

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