1.02442
氯仿
for analysis (for determinations with dithizone)
别名:
三氯甲烷
选择尺寸
关于此项目
产品名称
氯仿, for analysis (for determinations with dithizone)
InChI
1S/CHCl3/c2-1(3)4/h1H
SMILES string
ClC(Cl)Cl
InChI key
HEDRZPFGACZZDS-UHFFFAOYSA-N
vapor density
4.1 (vs air)
vapor pressure
160 mmHg ( 20 °C)
assay
99.0-99.4% (GC)
form
liquid
potency
695 mg/kg LD50, oral (Rat)
>3980 mg/kg LD50, skin (Rabbit)
dilution
(for analytical testing)
impurities
≤0.0001% Chloride (Cl)
≤0.001% Free acid (as HCl)
≤0.005% Carbonyl compounds (as CO)
≤0.01% Carbon tetrachloride (GC)
≤0.01% Dichloromethane (GC)
≤0.01% Tetrachloroethylene (GC)
≤0.01% Trichloroethylene (GC)
≤0.01% Water
0.6-1% Ethanol (GC)
0.6-1.0% Ethanol (GC)
evapn. residue
≤0.001%
refractive index
n20/D 1.445 (lit.)
bp
60.5-61.5 °C (lit.)
mp
−63 °C (lit.)
density
1.492 g/mL at 25 °C (lit.)
cation traces
Al: ≤0.00005%
B: ≤0.000002%
Ba: ≤0.00001%
Ca: ≤0.00005%
Cd: ≤0.000005%
Co: ≤0.000002%
Cr: ≤0.000002%
Cu: ≤0.000002%
Fe: ≤0.00001%
Mg: ≤0.00001%
Mn: ≤0.000002%
Ni: ≤0.000002%
Pb: ≤0.00001%
Sn: ≤0.00001%
Zn: ≤0.00001%
storage temp.
2-30°C
Quality Level
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Application
- Characterization of Natural Products: Chloroform is extensively used in the extraction and isolation of natural products. A study on the characterization and pesticidal evaluation of diterpenes isolated from chloroform extracts of Hedychium spicatum rhizomes highlights its effectiveness. This application is crucial for identifying bioactive compounds and assessing their potential uses in pharmaceuticals and agrochemicals (Rawat et al., Analytical Chemistry Letters, 2023).
- Self-Diffusion and Molecular Association Studies: Chloroform is used in studies of self-diffusion and molecular association in binary systems, such as dimethyl sulfoxide (DMSO) and acetone. These studies provide insights into the molecular interactions and dynamics in mixed solvents, which are essential for understanding solvation and reaction mechanisms in various chemical processes (Gurina and Golubev, Results in Chemistry, 2022).
- Cell-Free DNA Isolation: A novel phenol-chloroform-free method for isolating cell-free DNA from cell-conditioned media has been developed, optimized, and compared with traditional methods. This advancement is significant for genomic studies, allowing for more efficient and less hazardous extraction of nucleic acids from biological samples (Das et al., Analytical Biochemistry, 2024).
- Green Chemistry and Circular Economy: Chloroform plays a role in green analytical chemistry, particularly in the development of circular chemistry principles. Research emphasizes the need to design chemical processes that minimize waste and environmental impact, promoting sustainability in analytical laboratories. This includes the use of chloroform in recyclable and reusable systems to reduce solvent waste (Psillakis and Pena-Pereira, TrAC Trends in Analytical Chemistry, 2024).
Other Notes
signalword
Danger
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
target_organs
Central nervous system
存储类别
6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
wgk
WGK 3
flash_point_f
does not flash
flash_point_c
does not flash
法规信息
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