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Merck
CN

1.00164

SAFC

硼酸

cryst., EMPROVE® API, Ph. Eur., BP, NF

制药生产

别名:

Orthoboric acid, Trihydroxidoboron

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About This Item

线性分子式:
H3BO3
CAS号:
分子量:
61.83
MDL编号:
UNSPSC代码:
12352106
EC索引号:
233-139-2

Agency

BP
NF
Ph. Eur.

质量水平

蒸汽压

2.6 mmHg ( 20 °C)

产品线

EMPROVE® API

检测方案

99.5-100.5% (alkalimetric)

形式

solid

效能

2660 mg/kg LD50, oral (Rat)
>2000 mg/kg LD50, skin (Rat)

pH值(酸碱度)

3.8-4.8 (20 °C, 33 g/L in H2O)

mp

160 °C (dec.) (lit.)

溶解性

49.2 g/L

密度

1.489 g/cm3 at 23 °C

堆积密度

400‑600 kg/m3

痕量阴离子

sulfate (SO42-): ≤0.04%

痕量阳离子

As: ≤0.0001%
heavy metals (as Pb): ≤0.0015%

应用

liquid formulation
ophthalmics
parenterals
pharmaceutical
semi-solid formulation

储存温度

2-25°C

SMILES字符串

OB(O)O

InChI

1S/BH3O3/c2-1(3)4/h2-4H

InChI key

KGBXLFKZBHKPEV-UHFFFAOYSA-N

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相关类别

一般描述

We provide industry-leading production know-how and comprehensive regulatory support for high-quality APIs, backed by nearly 200 years of experience. From a complete portfolio of innovative folates to custom synthesis, our customized and scalable solutions meet your specific production needs. As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

应用

Boric acid as an active ingredient is used in ophthalmic drugs, as antiseptic for cuts and burns, as well as antibacterial for dermatological treatments such as acne and athlete foot. Boric acid Emprove® API is manufactured according to ICH Q7 guidelines. A CEP and an US-DMF are available.

法律信息

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

象形图

Health hazard

警示用语:

Danger

危险声明

危险分类

Repr. 1B

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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