1.00164
硼酸
cryst., EMPROVE® API, Ph. Eur., BP, NF
别名:
Orthoboric acid, Trihydroxidoboron
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关于此项目
线性分子式:
H3BO3
化学文摘社编号:
分子量:
61.83
UNSPSC Code:
12352106
EC Index Number:
233-139-2
MDL number:
产品名称
硼酸, cryst., EMPROVE® API, Ph. Eur., BP, NF
InChI
1S/BH3O3/c2-1(3)4/h2-4H
SMILES string
OB(O)O
InChI key
KGBXLFKZBHKPEV-UHFFFAOYSA-N
agency
BP
NF
Ph. Eur.
vapor pressure
2.6 mmHg ( 20 °C)
product line
EMPROVE® API
assay
99.5-100.5% (alkalimetric)
form
solid
potency
2660 mg/kg LD50, oral (Rat)
>2000 mg/kg LD50, skin (Rat)
pH
3.8-4.8 (20 °C, 33 g/L in H2O)
mp
160 °C (dec.) (lit.)
solubility
49.2 g/L
density
1.489 g/cm3 at 23 °C
bulk density
400‑600 kg/m3
anion traces
sulfate (SO42-): ≤0.04%
cation traces
As: ≤0.0001%
heavy metals (as Pb): ≤0.0015%
application(s)
liquid formulation
ophthalmics
parenterals
pharmaceutical
semi-solid formulation
storage temp.
2-25°C
Quality Level
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Application
Boric acid as an active ingredient is used in ophthalmic drugs, as antiseptic for cuts and burns, as well as antibacterial for dermatological treatments such as acne and athlete foot. Boric acid Emprove® API is manufactured according to ICH Q7 guidelines. A CEP and an US-DMF are available.
General description
We provide industry-leading production know-how and comprehensive regulatory support for high-quality APIs, backed by nearly 200 years of experience. From a complete portfolio of innovative folates to custom synthesis, our customized and scalable solutions meet your specific production needs. As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.
Legal Information
Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Danger
hcodes
Hazard Classifications
Repr. 1B
存储类别
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
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