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安全信息

1.00162

SAFC

硼酸

powder, EMPROVE® ESSENTIAL, Ph. Eur., BP, JP, NF

制药生产

别名:

Orthoboric acid, Trihydroxidoboron

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About This Item

线性分子式:
H3BO3
CAS号:
10043-35-3
分子量:
61.83
MDL编号:
MFCD00011337
UNSPSC代码:
12352301
EC索引号:
233-139-2

Agency

BP
JP
NF
Ph. Eur.

质量水平

500

蒸汽压

2.6 mmHg ( 20 °C)

产品线

EMPROVE® ESSENTIAL

方案

99.5-100.5% dry basis (alkalimetric)

表单

powder
solid

pH值（酸碱度）

3.8-4.8 (20 °C, 33 g/L in H2O)

mp

160 °C (dec.) (lit.)

溶解性

49.2 g/L

密度

1.489 g/cm3 at 23 °C

痕量阴离子

sulfate (SO42-): ≤0.04%

痕量阳离子

As: ≤0.0001%
heavy metals (as Pb): ≤0.0015%

应用

liquid formulation
ophthalmics
pharmaceutical
semi-solid formulation

储存温度

2-30°C

SMILES字符串

OB(O)O

InChI

1S/BH3O3/c2-1(3)4/h2-4H

InChI key

KGBXLFKZBHKPEV-UHFFFAOYSA-N

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一般描述

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

应用

Boric acid has antimicrobial characteristics and is therefore typically used as preservative in pharmaceutical formulations and cosmetics. It is also used as buffering agent and pH adjuster.

法律信息

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

相关产品

产品编号
说明
价格

象形图

Health hazard
GHS08

警示用语：

Danger

危险声明

H360FD

危险分类

Repr. 1B

储存分类代码

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

危险化学品

分析证书(COA)

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Criteria for Selecting Preservatives Used in Liquid Formulation

Find key considerations for the selection and use of preservatives in a range of different therapeutic applications including topical, oral, transmucosal, inhalation, and otic, as well as injectables.

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