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Merck
CN

1.00130

SAFC

苯甲酸

powder, EMPROVE® ESSENTIAL, Ph. Eur., BP, USP, E 210

Pharma Manufacturing

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别名:
Benzoic acid, Phenylformic acid, Benzene carboxylic acid
经验公式(希尔记法):
C7H6O2
CAS号:
分子量:
122.12
UNSPSC代码:
12352106
E编号:
E210
EC索引号:
200-618-2

Agency

BP
Ph. Eur.
USP

质量水平

蒸汽压

0.001 hPa ( 20 °C)

产品线

EMPROVE® ESSENTIAL

检测方案

99.5-100.5% substance (anhydrous) basis (acidimetric)

形式

powder
solid

自燃温度

570 °C

质量

E 210

技术

API processing | cocrystal formation: suitable
API processing | salt formation: suitable

pH值(酸碱度)

2.5-3.5 (20 °C in H2O, saturated solution)

bp

249 °C/1013 hPa

mp

121-123 °C

转变温度

flash point 121 °C

溶解性

water: 2.9 g/L at 25 °C

密度

1.321 g/cm3 at 20 °C

痕量阴离子

sulfate (SO42-): ≤0.02%

痕量阳离子

As: ≤1 ppm
Cd: ≤10 ppm
Cr: ≤2.5 ppm
Cu: ≤10 ppm
Hg: ≤1 ppm
Mn: ≤25 ppm
Ni: ≤2 ppm
Pb: ≤2 ppm
Zn: ≤10 ppm

应用

liquid formulation
pharmaceutical
semi-solid formulation

储存温度

15-25°C

InChI

1S/C7H6O2/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H,8,9)

InChI key

WPYMKLBDIGXBTP-UHFFFAOYSA-N

一般描述

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

应用

Benzoic acid is typically used as a preservative in pharmaceutical formulations and cosmetics due to its antimicrobial characteristics. It is also used as an additive for the preservation of food.

法律信息

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.

象形图

Health hazardCorrosion

警示用语:

Danger

危险声明

危险分类

Eye Dam. 1 - Skin Irrit. 2 - STOT RE 1 Inhalation

靶器官

Lungs

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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商品

Find key considerations for the selection and use of preservatives in a range of different therapeutic applications including topical, oral, transmucosal, inhalation, and otic, as well as injectables.

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