产品名称
抗-二甲基精氨酸抗体，非对称性（ASYM25）, serum, from rabbit
biological source
rabbit
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity
mouse
species reactivity (predicted by homology)
rat (based on 100% sequence homology), human (based on 100% sequence homology)
technique(s)
western blot: suitable
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Analysis Note
对照
经PRMT1处理和未处理的MEF细胞裂解液
经PRMT1处理和未处理的MEF细胞裂解液
已通过蛋白质印迹法在经PRMT1处理和未经处理的MEF细胞裂解液中进行了评估。
蛋白质印迹分析：该抗体的1:1,000稀释液在10 µg 经PRMT1处理和未处理的MEF细胞裂解液上检测到二甲基化精氨酸。
蛋白质印迹分析：该抗体的1:1,000稀释液在10 µg 经PRMT1处理和未处理的MEF细胞裂解液上检测到二甲基化精氨酸。
Application
使用经验证可用于WB的不对称性抗二甲基精氨酸抗体（ASYM25）检测二甲基精氨酸。
Biochem/physiol Actions
该抗体可识别二甲基化精氨酸。
General description
不对称二甲基化精氨酸（ADMA）是一种内源性L-精氨酸代谢产物，由含有甲基化精氨酸的蛋白质的蛋白水解产生，并且是一氧化氮合酶（NOS）的已知抑制剂。在各种研究中，已经观察到ADMA在细胞运动和肌动蛋白细胞骨架中具有调节作用。ADMA水平升高与散发性FSGS、冠状动脉疾病、高血压、外周动脉闭塞性疾病、肥胖、卒中、先兆子痫和糖尿病肾病患者的心血管死亡率/发病率相关。
多个。 该抗体可检测含有不对称二甲基化精氨酸的蛋白质。
Immunogen
含有不对称二甲基-精氨酸-甘氨酸重复序列的KLH偶联线性肽。
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存储类别
10 - Combustible liquids
wgk
WGK 1
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