推荐产品
生物来源
rabbit
质量水平
抗体形式
serum
抗体产品类型
primary antibodies
克隆
polyclonal
种属反应性
mouse
种属反应性（根据同源性预测）
rat (based on 100% sequence homology), human (based on 100% sequence homology)
技术
western blot: suitable
运输
wet ice
靶向翻译后修饰
unmodified
一般描述
不对称二甲基化精氨酸（ADMA）是一种内源性L-精氨酸代谢产物，由含有甲基化精氨酸的蛋白质的蛋白水解产生，并且是一氧化氮合酶（NOS）的已知抑制剂。在各种研究中，已经观察到ADMA在细胞运动和肌动蛋白细胞骨架中具有调节作用。ADMA水平升高与散发性FSGS、冠状动脉疾病、高血压、外周动脉闭塞性疾病、肥胖、卒中、先兆子痫和糖尿病肾病患者的心血管死亡率/发病率相关。
特异性
该抗体可识别二甲基化精氨酸。
免疫原
含有不对称二甲基-精氨酸-甘氨酸重复序列的KLH偶联线性肽。
应用
使用经验证可用于WB的不对称性抗二甲基精氨酸抗体（ASYM25）检测二甲基精氨酸。
质量
已通过蛋白质印迹法在经PRMT1处理和未经处理的MEF细胞裂解液中进行了评估。
蛋白质印迹分析：该抗体的1:1,000稀释液在10 µg 经PRMT1处理和未处理的MEF细胞裂解液上检测到二甲基化精氨酸。
蛋白质印迹分析：该抗体的1:1,000稀释液在10 µg 经PRMT1处理和未处理的MEF细胞裂解液上检测到二甲基化精氨酸。
目标描述
多个。 该抗体可检测含有不对称二甲基化精氨酸的蛋白质。
分析说明
对照
经PRMT1处理和未处理的MEF细胞裂解液
经PRMT1处理和未处理的MEF细胞裂解液
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储存分类代码
10 - Combustible liquids
WGK
WGK 1
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