产品名称
Anti-HRI Antibody, serum, Upstate®
biological source
rabbit
conjugate
unconjugated
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity
rabbit, human, mouse
manufacturer/tradename
Upstate®
technique(s)
immunoprecipitation (IP): suitable
western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... EIF2AK1(27102)
mouse ... Eif2Ak1(15467)
Analysis Note
Routinely evaluated by immunoblot on lysates from mouse reticulocytes.
Application
Detect HRI using this Anti-HRI Antibody validated for use in IP & WB.
Biochem/physiol Actions
HRI
General description
72kDa
Immunogen
6His-tagged fusion protein corres-ponding to residues 1-138 of mouse heme-regulated inhibitor (HRI)
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
未找到合适的产品？
试试我们的产品选型工具.
存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Visibly stressed: the role of eIF2, TIA-1, and stress granules in protein translation.
Anderson, Paul and Kedersha, Nancy
Cell Stress & Chaperones, 7, 213-221 (2002)
Nicolò Musner et al.
ASN neuro, 8(2) (2016-04-21)
In peripheral nerves, P0 glycoprotein accounts for more than 20% of myelin protein content. P0 is synthesized by Schwann cells, processed in the endoplasmic reticulum (ER) and enters the secretory pathway. However, the mutant P0 with S63 deleted (P0S63del) accumulates
Maryam Rafie-Kolpin et al.
Biochemistry, 42(21), 6536-6544 (2003-05-28)
In heme deficiency, protein synthesis is inhibited by the activation of the heme-regulated eIF2alpha kinase (HRI) through its multiple autophosphorylation. Autophosphorylation sites in HRI were identified in order to investigate their functions. We found that there were eight major tryptic
The eIF-2alpha kinases and the control of protein synthesis.
de Haro, C, et al.
Faseb Journal, 10, 1378-1387 (1996)
Takahiro Sakai et al.
Antioxidants (Basel, Switzerland), 10(9) (2021-09-29)
Lung fibrosis is the primary pathology in idiopathic pulmonary fibrosis and is considered to result from an increase in reactive oxygen species (ROS) levels in alveolar epithelial cells. However, the exact mechanism underlying lung fibrosis remains unclear and there is
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持