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生物来源
rabbit
质量水平
抗体形式
purified antibody
抗体产品类型
primary antibodies
克隆
polyclonal
种属反应性
mouse, human, rat
制造商/商品名称
Upstate®
技术
western blot: suitable
同位素/亚型
IgG
NCBI登记号
UniProt登记号
运输
dry ice
靶向翻译后修饰
unmodified
基因信息
mouse ... Lingo1(235402)
特异性
LINGO-1
免疫原
KLH-conjugated, synthetic peptide corresponding to amino acid residues 611-620 of human LINGO-1 (APRKFNMKMI)
应用
Detect LINGO-1 using this Anti-LINGO-1 Antibody validated for use in WB.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurodegenerative Diseases
Neurodegenerative Diseases
质量
routinely evaluated by immunoblot on mouse brain membrane samples.
目标描述
Mr ~83kDa
外形
Protein A purified
Format: Purified
储存及稳定性
stable for 2 years at -20°C from date of shipment
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
WGK
WGK 2
Lingo-1 expression is increased in essential tremor cerebellum and is present in the basket cell pinceau.
Kuo, SH; Tang, G; Louis, ED; Ma, K; Babji, R; Balatbat, M; Cortes, E; Vonsattel et al.
Acta neuropathologica null
Sha Mi et al.
Nature neuroscience, 7(3), 221-228 (2004-02-18)
Axon regeneration in the adult CNS is prevented by inhibitors in myelin. These inhibitors seem to modulate RhoA activity by binding to a receptor complex comprising a ligand-binding subunit (the Nogo-66 receptor NgR1) and a signal transducing subunit (the neurotrophin
Alexandra Trifunovski et al.
Neuroreport, 15(15), 2397-2400 (2005-01-11)
Axonal regeneration after injury can be limited in the adult CNS by the presence of inhibitory proteins such as Nogo. Nogo binds to a receptor complex that consists of Nogo receptor (NgR), p75NTR, and Lingo-1. Nogo binding activates RhoA, which
Multi-tasking by the p75 neurotrophin receptor: sortilin things out?
Bronfman, Francisca C and Fainzilber, Mike
EMBO Reports, 5, 867-871 (2004)
TROY and LINGO-1 expression in astrocytes and macrophages/microglia in multiple sclerosis lesions.
J Satoh, H Tabunoki, T Yamamura, K Arima, H Konno
Neuropathology and Applied Neurobiology null
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