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Merck
CN
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主要文件

07-625

Sigma-Aldrich

Anti-ATRIP Antibody

Upstate®, from rabbit

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About This Item

UNSPSC代码:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物来源

rabbit

质量水平

抗体形式

purified immunoglobulin

抗体产品类型

primary antibodies

克隆

polyclonal

种属反应性

human

制造商/商品名称

Upstate®

技术

immunocytochemistry: suitable
western blot: suitable

同位素/亚型

IgG

GenBank登记号

UniProt登记号

运输

wet ice

靶向翻译后修饰

unmodified

基因信息

human ... ATRIP(84126)

一般描述

Antibody recognizing ATR-Interacting Protein

特异性

ATRIP

免疫原

GST fusion protein corresponding to residues 1-181 of human ATR interacting protein (ATRIP)

应用

Detect ATRIP with Anti-ATRIP Antibody (Rabbit Polyclonal Antibody), that has been shown to work in WB, ICC.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Cell Cycle, DNA Replication & Repair

质量

Routinely evaluated by immunoblot on modified RIPA lysates from HEK293, HeLa and U20S cells

目标描述

85kDa

外形

Protein G Purified
70% storage buffer (0.05M Tris-glycine, 0.025M sodium phosphate, pH 7.4, 0.15M NaCl, 0.035% sodium azide) and 30% glycerol
Format: Purified

储存及稳定性

2 years at -20°C

法律信息

GenBank is a registered trademark of United States Department of Health and Human Services
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

10 - Combustible liquids

WGK

WGK 1


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D Cortez et al.
Science (New York, N.Y.), 294(5547), 1713-1716 (2001-11-27)
The checkpoint kinases ATM (ataxia telangiectasia mutated) and ATR (ATM and Rad3 related) transduce genomic stress signals to halt cell cycle progression and promote DNA repair. We report the identification of an ATR-interacting protein (ATRIP) that is phosphorylated by ATR
Lee Zou et al.
Science (New York, N.Y.), 300(5625), 1542-1548 (2003-06-07)
The function of the ATR (ataxia-telangiectasia mutated- and Rad3-related)-ATRIP (ATR-interacting protein) protein kinase complex is crucial for the cellular response to replication stress and DNA damage. Here, we show that replication protein A (RPA), a protein complex that associates with
Qiang Li et al.
PloS one, 5(10), e13732-e13732 (2010-11-10)
H3K9 trimethylation (H3K9me3) and binding of PcG repressor complex-1 (PRC1) may play crucial roles in the epigenetic silencing of the p16 gene. However, the mechanism of the initiation of this trimethylation is unknown. In the present study, we found that
Janna Luessing et al.
iScience, 25(7), 104536-104536 (2022-06-28)
Abscission, the final stage of cytokinesis, occurs when the cytoplasmic canal connecting two emerging daughter cells is severed either side of a large proteinaceous structure, the midbody. Here, we expand the functions of ATR to include a cell-cycle-specific role in
Richard O Adeyemi et al.
Journal of virology, 88(17), 10189-10199 (2014-06-27)
The ATR kinase has essential functions in maintenance of genome integrity in response to replication stress. ATR is recruited to RPA-coated single-stranded DNA at DNA damage sites via its interacting partner, ATRIP, which binds to the large subunit of RPA.

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