07-618
抗-SF-1抗体
Upstate®, from rabbit
别名:
Anti-AD4BP, Anti-FTZ1, Anti-FTZF1, Anti-POF7, Anti-SF-1, Anti-SF1, Anti-SPGF8, Anti-SRXX4, Anti-SRXY3, Anti-hSF-1
产品名称
抗-SF-1抗体, Upstate®, from rabbit
biological source
rabbit
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
species reactivity
mouse
manufacturer/tradename
Upstate®
technique(s)
western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... NR5A1(2516), SF1(7536)
Analysis Note
对照
Y1细胞裂解液
Y1细胞裂解液
通过免疫印迹对Y1细胞的RIPA裂解液进行了常规评估
Application
抗-SF-1抗体是一种高质量的兔多克隆抗体，用于检测SF-1，&已在WB中得到验证。
研究子类别
转录因子
转录因子
研究类别
表观遗传学&核功能
表观遗传学&核功能
Biochem/physiol Actions
识别SF-1。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
53kda
甾体生成因子-1（SF-1）调节参与肾上腺和性腺发育的多个基因，并参与多种激素的生物合成，包括肾上腺和性腺类固醇、抗苗勒管激素（AMH）和促性腺激素。SF-1属于孤儿核受体Fushi Tarazu因子-1（FTZ-F1）亚家族。在成人卵巢中，SF-1定位于膜/间质细胞。
Immunogen
小鼠SF-1的DNA结合域，在大肠杆菌中作为GST融合蛋白产生，通过GST琼脂糖柱层析部分纯化
Other Notes
浓度：请参考批次特异性浓缩物的检验报告。
Physical form
形式：纯化
纯化蛋白A
蛋白A纯化的免疫球蛋白，溶于30％甘油，0.07M Tris-甘氨酸（pH 7.4）、0.105 M NaCl，0.035％叠氮化钠作为防腐剂的溶液中。
Preparation Note
自收到之日起在-20°C可稳定保存2年。避免反复冻融。为了最大程度地回收产品，在融化后和取下盖子之前，将原始小瓶进行离心。
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
10 - Combustible liquids
wgk
WGK 2
Giulia Cantini et al.
Cancers, 12(11) (2020-11-04)
Adrenocortical carcinoma (ACC), a rare and aggressive neoplasia, presents poor prognosis when metastatic at diagnosis and limited therapies are available. Specific and sensitive markers for early diagnosis and a monitoring system of therapy and tumor evolution are urgently needed. The
Steroidogenic factor 1: an essential mediator of endocrine development
Parker, Keith L, et al
Recent Progress in Hormone Research, 57, 19-36 (2002)
Francesca Salvianti et al.
Oncotarget, 8(39), 65525-65533 (2017-10-17)
Adrenocortical cancer (ACC) is a rare aggressive malignancy. Recent ACC integrated genomics analysis contributed to redefine the risk groups on molecular basis, including tumor microRNAs (miRs), detectable also in the bloodstream. We developed a quantitative real-time (RT) assay for the
Hormonal regulation of microRNA expression in steroid producing cells of the ovary, testis and adrenal gland.
Hu, Z; Shen, WJ; Cortez, Y; Tang, X; Liu, LF; Kraemer, FB; Azhar, S
Testing null
Steroidogenic factor-1: a key regulator of gonadotroph gene expression
Fowkes, R C and Burrin, J M
The Journal of Endocrinology, 177, 345-350 (2003)
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