产品名称
抗二甲基组蛋白H3(Arg2)抗体, serum, Upstate®
biological source
rabbit
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity
human, chicken
manufacturer/tradename
Upstate®
technique(s)
inhibition assay: suitable (peptide)
western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
dimethylation (Arg2)
Quality Level
Gene Information
human ... H3F3B(3021)
Analysis Note
通过免疫印迹法对鸡红细胞(目录号13-107)的酸提取蛋白进行常规评估
Application
抗二甲基化组蛋白H3(Arg2)抗体是一种兔多克隆抗体,用于检测二甲基化组蛋白H3(Arg2),也称为H3R2me2,组蛋白H3(二甲基R2),& 已在WB,PIA中进行了验证。
研究子类别
组蛋白
组蛋白
研究类别
表观遗传学&核功能
表观遗传学&核功能
Biochem/physiol Actions
组蛋白H3残基2的二甲基精氨酸
预计具有广泛的物种交叉反应性
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
Mr 17kDa
Immunogen
一种含有序列AdimRT的肽,对应于人组蛋白H3的二甲基-精氨酸2
Physical form
兔抗血清,含有0.05%叠氮化钠,然后添加甘油至30%
血清
Preparation Note
在-20°C下可保存2年
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Haolin Liu et al.
Proceedings of the National Academy of Sciences of the United States of America, 114(37), E7717-E7726 (2017-08-30)
Two of the unsolved, important questions about epigenetics are: do histone arginine demethylases exist, and is the removal of histone tails by proteolysis a major epigenetic modification process? Here, we report that two orphan Jumonji C domain (JmjC)-containing proteins, JMJD5
Claudia Stein et al.
Nucleic acids research, 40(19), 9522-9533 (2012-08-21)
The protein arginine methyltransferase 6 (PRMT6) is a coregulator of gene expression and executes its repressing as well as activating function by asymmetric dimethylation of histone H3 at R2 (H3 R2me2a). Given that elevated expression levels of PRMT6 have been
PELP1 oncogenic functions involve alternative splicing via PRMT6.
Mann, M; Zou, Y; Chen, Y; Brann, D; Vadlamudi, R
Molecular Oncology null
Jihee Hong et al.
Journal of ginseng research, 46(3), 481-488 (2022-05-24)
Although the tumor-suppressive effects of ginsenosides in cell cycle have been well established, their pharmacological properties in mitosis have not been clarified yet. The chromosomal instability resulting from dysregulated mitotic processes is usually increased in cancer. In this study, we
Sinja Rakow et al.
Methods (San Diego, Calif.), 175, 53-65 (2019-09-23)
Among the widespread and increasing number of identified post-translational modifications (PTMs), arginine methylation is catalyzed by the protein arginine methyltransferases (PRMTs) and regulates fundamental processes in cells, such as gene regulation, RNA processing, translation, and signal transduction. As epigenetic regulators
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