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Merck
CN

07-551

抗G9a抗体

Upstate®, from rabbit

别名:

KMT1C

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
western blot
Species reactivity:
human
Citations:
50
Technique(s):
western blot: suitable
Uniprot accession no.:
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产品名称

抗G9a抗体, Upstate®, from rabbit

biological source

rabbit

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human

packaging

antibody small pack of 25 μg

manufacturer/tradename

Upstate®

technique(s)

western blot: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Quality Level

Gene Information

human ... EHMT2(10919)

Analysis Note

对照
阳性抗原对照:货号12-309,HeLa细胞核提取物。添加 等体积Laemmli样品还原性缓冲液至10 μL提取物并 煮沸5分钟以还原制剂。在小型凝胶每个泳道上样20 μg 经还原的提取物。
对照
阳性对照包括:HeLa 核提取物(12-309)。
通过免疫印迹对 HeLa 核提取细胞裂解液进行了常规评估

Application

使用在 WB 中验证的抗 G9a 抗体(兔多克隆抗体)检测 G9a(也称为 KMT1C)。
研究子类别
组蛋白
研究类别
表观遗传学&核功能

Biochem/physiol Actions

识别人 G9a 蛋白。

Disclaimer

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

General description

140kda
蛋白 G9a(也称为组蛋白 H3-K9 甲基转移酶 3,常染色体组蛋白赖氨酸 N-甲基转移酶 2 和 HLA-B 相关转录本 8)

Immunogen

对应于人 G9a 氨基酸 71-88 的肽(C-DERVDSDSKSEVEALTEQ)。

Other Notes

浓度:请参考批次特异性浓缩物的分析证书。

Physical form

在 30% 甘油,0.07M Tris-甘氨酸,pH 7.4、0.105 M NaCl,0.035% 叠氮化钠作为防腐剂的溶液中的蛋白 A 纯化的免疫球蛋白。
形式:纯化的
纯化的蛋白 A

Preparation Note

自发货之日起,在 -20°C 条件下可稳定保存 2 年。等分试样,避免反复冻融。为最大程度地回收产品,在打开瓶盖之前先将小瓶离心。

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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存储类别

10 - Combustible liquids

wgk

WGK 2


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Changes in C-terminal binding protein 2 (CtBP2) corepressor complex induced by E1A and modulation of E1A transcriptional activity by CtBP2.
Zhao, LJ; Subramanian, T; Chinnadurai, G
The Journal of Biological Chemistry null
Role of the PLDLS-binding cleft region of CtBP1 in recruitment of core and auxiliary components of the corepressor complex.
Kuppuswamy, M; Vijayalingam, S; Zhao, LJ; Zhou, Y; Subramanian, T; Ryerse, J; Chinnadurai, G
Molecular and cellular biology null
Gfi1 coordinates epigenetic repression of p21Cip/WAF1 by recruitment of histone lysine methyltransferase G9a and histone deacetylase 1.
Duan, Z; Zarebski, A; Montoya-Durango, D; Grimes, HL; Horwitz, M
Molecular and cellular biology null
Mihai G Mehedint et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 24(1), 184-195 (2009-09-16)
Maternal choline availability is essential for fetal neurogenesis. Choline deprivation (CD) causes hypomethylation of specific CpG islands in genes controlling cell cycling in fetal hippocampus. We now report that, in C57BL/6 mice, CD during gestational days 12-17 also altered methylation
Hyeonsoo Jung et al.
Scientific reports, 7, 46182-46182 (2017-04-08)
Recent studies have reported the ectopic expression of olfactory receptors (ORs) in non-olfactory tissues, however, their physiological roles were not well elucidated. ORs are expressed in and function in different types of cancers. Here, we identified that the H3K9me2 levels

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