跳转至内容
Merck
CN
所有图片(1)

文件

07-524

Sigma-Aldrich

Anti-Spry2 Antibody

Upstate®, from rabbit

登录查看公司和协议定价


About This Item

UNSPSC代码:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物来源

rabbit

质量水平

抗体形式

purified immunoglobulin

抗体产品类型

primary antibodies

克隆

polyclonal

种属反应性

human, rat

制造商/商品名称

Upstate®

技术

western blot: suitable

同位素/亚型

IgG

NCBI登记号

UniProt登记号

运输

dry ice

靶向翻译后修饰

unmodified

基因信息

human ... SPRY2(10253)

特异性

Recognizes SPROUTY2.

免疫原

Peptide corresponding to amino acids 26-39 of human SPROUTY2

应用

Detect Spry2 using this Anti-Spry2 Antibody validated for use in WB.
Research Category
Signaling
Research Sub Category
Growth Factors & Receptors

Kinases & Phosphatases

质量

routinely evaluated by immunoblot in in RIPA lysates from HeLa and 3T3/A31

目标描述

35-40 kDa

外形

Protein A purified
Format: Purified
Protein A Purified immunoglobulin in 30% glycerol, 0.07M Tris-glycine, pH 7.4, 0.105 M NaCl, 0.035% sodium azide as a preservative.

储存及稳定性

Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

分析说明

Control
Positive Antigen Control: Catalog #12-305, 3T3/A31 lysate. Add 2.5 μL of 2-mercapto-ethanol/100 μL of lysate and boil for 5 minutes to reduce the preparation. Load 20 μg of reduced lysate per lane for minigels.

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律信息

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Not finding the right product?  

Try our 产品选型工具.

储存分类代码

12 - Non Combustible Liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable


分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

Weimin Liu et al.
The Journal of allergy and clinical immunology, 121(4), 893-902 (2008-04-09)
Many airway cells manifest signs of chronic activation in asthma. The mechanism of this chronic activation is unknown. We sought to study the activation of the mitogen-activated protein kinase (MAPK) signaling pathway in airway cells. Endobronchial biopsy specimens from patients
N Hacohen et al.
Cell, 92(2), 253-263 (1998-02-11)
Antagonists of several growth factor signaling pathways play important roles in developmental patterning by limiting the range of the cognate inducer. Here, we describe an antagonist of FGF signaling that patterns apical branching of the Drosophila airways. In wild-type embryos
Permeen Yusoff et al.
The Journal of biological chemistry, 277(5), 3195-3201 (2001-11-08)
Several genetic studies in Drosophila have shown that the dSprouty (dSpry) protein inhibits the Ras/mitogen-activated protein (MAP) kinase pathway induced by various activated receptor tyrosine kinase receptors, most notably those of the epidermal growth factor receptor (EGFR) and fibroblast growth
Concomitant down-regulation of SPRY1 and SPRY2 in prostate carcinoma.
Fritzsche, S; Kenzelmann, M; Hoffmann, MJ; Muller, M; Engers, R; Grone, HJ; Schulz, WA
Endocrine-Related Cancer null
Hiroshi Hanafusa et al.
Nature cell biology, 4(11), 850-858 (2002-10-29)
Sprouty (Spry) inhibits signalling by receptor tyrosine kinases; however, the molecular mechanism underlying this function has not been defined. Here we show that after stimulation by growth factors Spry1 and Spry2 translocate to the plasma membrane and become phosphorylated on

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门