推荐产品
生物来源
rabbit
质量水平
抗体形式
purified antibody
抗体产品类型
primary antibodies
克隆
polyclonal
种属反应性
human, mouse
制造商/商品名称
Upstate®
技术
western blot: suitable
同位素/亚型
IgG
运输
dry ice
靶向翻译后修饰
unmodified
一般描述
对称二甲基化精氨酸（sDMA）是翻译后修饰精氨酸甲基化的产物。sDMA是不对称二甲基精氨酸的结构异构体。
特异性
约16 kDa处的SmD3和其他含有对称二甲基化精氨酸的蛋白质
免疫原
一种对应于小核糖核蛋白Smd3的99-119位氨基酸的肽。
应用
对称抗二甲基精氨酸抗体（SYM11）已用于：
- 免疫共沉淀
- 蛋白质印迹分析
- 免疫沉淀
生化/生理作用
对称二甲基精氨酸（sDMA）是精氨酸转运的竞争对手，通过肾脏排泄被消除。sDMA作为指示估计肾小球滤过率（GFR）和冠状动脉疾病（CAD）严重程度的标志物。sDMA升高与心血管疾病和死亡率的风险相关。它也可能有助于早期发现慢性肾脏疾病。sDMA是肾功能的内源性标志物。它与肿瘤发生有关。
质量
通过免疫印迹对Jurkat细胞的RIPA裂解液进行了常规评估
目标描述
~16 kDa
外形
形式：纯化
分析说明
对照
阳性抗原对照：目录# 12-303，Jurkat细胞裂解液。
阳性抗原对照：目录# 12-303，Jurkat细胞裂解液。
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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储存分类代码
10 - Combustible liquids
WGK
WGK 1
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