产品名称
Anti-WAVE2/Scar2 Antibody, serum, Upstate®
biological source
rabbit
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity
rat, human
manufacturer/tradename
Upstate®
technique(s)
western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... WASF2(10163)
Analysis Note
routinely evaluated by immunoblot in in RIPA lysates from HL60 cells
Application
Research Category
Signaling
Signaling
Research Sub Category
Cytoskeletal Signaling
Cytoskeletal Signaling
This Anti-WAVE2/Scar2 Antibody is validated for use in WB for the detection of WAVE2/Scar2.
Biochem/physiol Actions
WAVE2/Scar2
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
~68kDa
Immunogen
peptide corresponding to amino acids 186-200 of human WAVE2/Scar2, with an N-terminal cysteine
Physical form
0.05% sodium azide before the addition of glycerol to 30%
Antiserum
Preparation Note
2 years at -20°C
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
L M Machesky et al.
Current biology : CB, 8(25), 1347-1356 (1999-01-16)
The actin-related proteins Arp2 and Arp3 are part of a seven-protein complex which is localized in the lamellipodia of a variety of cell types, and in actin-rich spots of unknown function. The Arp2/3 complex enhances actin nucleation and causes branching
Kun Li et al.
World journal of gastroenterology, 27(15), 1595-1615 (2021-05-08)
Expression of the full-length isoform of Abelson interactor 1 (ABI1), ABI1-p65, is increased in colorectal carcinoma (CRC) and is thought to be involved in one or more steps leading to tumor progression or metastasis. The ABI1 splice isoform-L (ABI1-SiL) has
S Suetsugu et al.
Biochemical and biophysical research communications, 260(1), 296-302 (1999-06-25)
WAVE/SCAR protein was identified as a protein which has similarity to WASP and N-WASP, especially in its C terminal. Recently, WAVE/SCAR protein has been shown to cooperate with the Arp2/3 complex, a nucleation core for actin polymerization in vitro. However
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