产品名称
抗磷酸化丝切蛋白2（Ser3）抗体, Upstate®, from rabbit
biological source
rabbit
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
species reactivity
mouse, chicken, human
manufacturer/tradename
Upstate®
technique(s)
western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
phosphorylation (pSer3)
Quality Level
Gene Information
human ... CFL2(1073)
Analysis Note
已通过免疫印迹对L6细胞（已用LIM激酶处理）的RIPA裂解液进行了常规评估
Application
抗磷酸-Cofilin 2（Ser3）抗体可检测磷酸化-Cofilin 2（Ser3）水平，已发布，经验证可用于WB。
研究子类别
细胞骨架
细胞骨架
研究类别
细胞结构
细胞结构
Biochem/physiol Actions
磷酸-Cofilin 2
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
21kDa
Immunogen
对应于人磷酸-Cofilin 2氨基酸1-10（MA[pS]GVTVNDE-C）的肽
Physical form
0.1M Tris-甘氨酸，pH 7.4，0.15M NaCl，0.05％叠氮化钠，然后添加甘油至30％
形式：纯化
蛋白A层析
Preparation Note
在-20°C下可保存2年
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
10 - Combustible liquids
wgk
WGK 1
Toru Amano et al.
The Journal of biological chemistry, 277(24), 22093-22102 (2002-04-02)
Actin filament dynamics play a critical role in mitosis and cytokinesis. LIM motif-containing protein kinase 1 (LIMK1) regulates actin reorganization by phosphorylating and inactivating cofilin, an actin-depolymerizing and -severing protein. To examine the role of LIMK1 and cofilin during the
C Thirion et al.
European journal of biochemistry, 268(12), 3473-3482 (2001-06-26)
Cofilins are actin binding proteins and regulate actin assembly in vivo. Numerous cofilin homologues have been characterized in various organisms including mammals. In mice, a ubiquitously expressed cofilin (CFL1) and a skeletal muscle specific cofilin (CFL2) have been described. In
J Craig Hunter et al.
Journal of molecular and cellular cardiology, 47(6), 810-818 (2009-10-06)
Although nitric oxide (NO) has received extensive attention as an anti-hypertrophic agent the mechanisms underlying its regulation of endothelin-1 (ET-1) have not been fully elucidated. Since RhoA has been identified as an important mediator of cardiac hypertrophy and is inhibited
Differential dependence of stretch and shear stress signaling on caveolin-1 in the vascular wall.
Albinsson, S; Nordstrom, I; Sward, K; Hellstrand, P
American Journal of Physiology. Cell Physiology null
Mardjaneh Sadegh Karbalaei et al.
European journal of pharmacology, 689(1-3), 179-185 (2012-05-31)
Caveolae are membrane invaginations present in a variety of cell types. Formation of caveolae depends on caveolins and on the more recently discovered family of proteins known as the cavins. Genetic ablation of caveolin-1 was previously shown to give rise
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