推荐产品
生物来源
rabbit
质量水平
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
纯化方式
affinity chromatography
种属反应性
bovine, rat, human, mouse
制造商/商品名称
Upstate®
技术
western blot: suitable
同位素/亚型
IgG
UniProt登记号
运输
wet ice
靶向翻译后修饰
unmodified
基因信息
human ... PPP2CA(5515)
特异性
PP2A催化亚基
免疫原
对应于人PP2A氨基酸290-304（DPAPRRGEPHVTRRT）的肽
应用
研究子类别
氧化应激
神经退行性疾病
氧化应激
神经退行性疾病
研究类别
信号传导
神经科学
信号传导
神经科学
该抗-PP2A抗体（C亚基）经过验证可用于WB检测PP2A。
质量
已通过免疫印迹对小鼠脑、心脏、睾丸和肾脏匀浆液的RIPA裂解液进行常规评估
目标描述
36kDa
外形
0.2M Tris-甘氨酸（pH 7.4）、0.15M NaCl、0.05％叠氮化钠、5mg/ml BSA，然后添加甘油至30％
免疫亲和层析
储存及稳定性
在-20°C下可保存2年
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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储存分类代码
10 - Combustible liquids
WGK
WGK 2
Satoru Kake et al.
Scientific reports, 7(1), 4279-4279 (2017-06-29)
Canine mammary tumor is the most common neoplasm in female dogs, and it has generated considerable attention as a translational model for human breast cancer. Ser/Thr protein phosphatase 2A (PP2A) plays a critical role as a tumor suppressor, and SET/I2PP2A
Jian Chen et al.
Plant physiology, 166(3), 1519-1534 (2014-10-05)
PROTEIN PHOSPHATASE 2A (PP2A) is a major group of serine/threonine protein phosphatases in eukaryotes. It is composed of three subunits: scaffolding subunit A, regulatory subunit B, and catalytic subunit C. Assembly of the PP2A holoenzyme in Arabidopsis (Arabidopsis thaliana) depends
Shunya Tsuji et al.
The Journal of veterinary medical science, 81(10), 1424-1430 (2019-09-19)
Osteosarcoma (OSA) is the most common bone tumor in dogs. Protein phosphatase 2A (PP2A), an evolutionary conserved serine/threonine protein phosphatase, is a crucial tumor suppressor. SET is a PP2A inhibitory protein that directly interacts with PP2A and suppresses its phosphatase
Characterization of SET/I2PP2A isoforms in dogs.
Yabe, R; Fujiwara, N; Mizuno, T; Usui, T; Ohama, T; Sato, K
The Journal of Veterinary Medical Science null
Sana Ando et al.
The Journal of biological chemistry, 300(5), 107277-107277 (2024-04-09)
Protein phosphatase 2A (PP2A) is an essential serine/threonine protein phosphatase, and its dysfunction is involved in the onset of cancer and neurodegenerative disorders. PP2A functions as a trimeric holoenzyme whose composition is regulated by the methyl-esterification (methylation) of the PP2A
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