07-324
抗-PP2A抗体（C亚基 ）
Upstate®, from rabbit
别名:
Anti-NEDLBA, Anti-PP2Ac, Anti-PP2CA, Anti-PP2Calpha, Anti-RP-C
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
western blot
Species reactivity:
bovine, rat, human, mouse
Citations:
16
Technique(s):
western blot: suitable
Uniprot accession no.:
产品名称
抗-PP2A抗体（C亚基 ）, Upstate®, from rabbit
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
bovine, rat, human, mouse
manufacturer/tradename
Upstate®
technique(s)
western blot: suitable
isotype
IgG
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... PPP2CA(5515)
Analysis Note
已通过免疫印迹对小鼠脑、心脏、睾丸和肾脏匀浆液的RIPA裂解液进行常规评估
Application
研究子类别
氧化应激
神经退行性疾病
氧化应激
神经退行性疾病
研究类别
信号传导
神经科学
信号传导
神经科学
该抗-PP2A抗体（C亚基）经过验证可用于WB检测PP2A。
Biochem/physiol Actions
PP2A催化亚基
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
36kDa
Immunogen
对应于人PP2A氨基酸290-304（DPAPRRGEPHVTRRT）的肽
Physical form
0.2M Tris-甘氨酸（pH 7.4）、0.15M NaCl、0.05％叠氮化钠、5mg/ml BSA，然后添加甘油至30％
免疫亲和层析
Preparation Note
在-20°C下可保存2年
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
10 - Combustible liquids
wgk
WGK 2
Satoru Kake et al.
Scientific reports, 7(1), 4279-4279 (2017-06-29)
Canine mammary tumor is the most common neoplasm in female dogs, and it has generated considerable attention as a translational model for human breast cancer. Ser/Thr protein phosphatase 2A (PP2A) plays a critical role as a tumor suppressor, and SET/I2PP2A
Rongbin Hu et al.
Plant, cell & environment, 40(1), 150-164 (2016-10-28)
Protein phosphatase 2A (PP2A) is an enzyme consisting of three subunits: a scaffolding A subunit, a regulatory B subunit and a catalytic C subunit. PP2As were shown to play diverse roles in eukaryotes. In this study, the function of the
Characterization of SET/I2PP2A isoforms in dogs.
Yabe, R; Fujiwara, N; Mizuno, T; Usui, T; Ohama, T; Sato, K
The Journal of Veterinary Medical Science null
Shunya Tsuji et al.
The Journal of veterinary medical science, 81(10), 1424-1430 (2019-09-19)
Osteosarcoma (OSA) is the most common bone tumor in dogs. Protein phosphatase 2A (PP2A), an evolutionary conserved serine/threonine protein phosphatase, is a crucial tumor suppressor. SET is a PP2A inhibitory protein that directly interacts with PP2A and suppresses its phosphatase
Nobuyuki Fujiwara et al.
Cancer science, 111(12), 4371-4380 (2020-09-25)
Protein phosphatase 6 (PP6) is an essential serine/threonine protein phosphatase that acts as an important tumor suppressor. However, increased protein levels of PP6 have been observed in some cancer types, and they correlate with poor prognosis in glioblastoma. This raises
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