推荐产品
生物来源
rabbit
质量水平
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
纯化方式
affinity chromatography
种属反应性
human, mouse
种属反应性（根据同源性预测）
rat (based on 100% sequence homology)
制造商/商品名称
Upstate®
技术
western blot: suitable
NCBI登记号
UniProt登记号
运输
wet ice
靶向翻译后修饰
unmodified
基因信息
human ... TACC2(10579)
一般描述
TACC2, also known as transforming acidic coiled-coil-containing protein 2, belongs to the transforming acidic coiled-coil-containing (TACC) protein family. This group of proteins is defined by its highly conserved coiled-coil domain. This domain is necessary for the assignment of the centrosome-spindle apparatus during cell cycling. There are three proteins belonging to the TACC family; TACC1, TACC2, and TACC3. TACC2 has been reported as playing a necessary role in cultured cell microtubule stabilization. It has also been shown that the binding of TACC2 by T antigen can cause chromosomal instability and mitotic defects (Tei, 2009). Research into the over expression of TACC2 strongly suggests a potential function as a tumor suppressor (Tei, 2009).
免疫原
KLH-conjugated linear peptide corresponding to the mature chain of mouse TACC2.
应用
Anti-TACC2 Antibody is a Rabbit Polyclonal Antibody for detection of TACC2 also known as transforming acidic coiled-coil containing protein 2 & has been validated in WB.
质量
Evaluated by Western Blot in mouse testis tissue lysate.
Western Blot Analysis: 2 µg/mL of this antibody detected TACC2 on 10 µg of mouse testis tissue lysate.
Western Blot Analysis: 2 µg/mL of this antibody detected TACC2 on 10 µg of mouse testis tissue lysate.
目标描述
Observed molecular weight, 73 kDa
Note this protein can be highly modified and several isoforms exist.
Note this protein can be highly modified and several isoforms exist.
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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储存分类代码
12 - Non Combustible Liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Molecular cloning, genomic structure and interactions of the putative breast tumor suppressor TACC2.
Brenda Lauffart, Omkaram Gangisetty, Ivan H Still
Genomics null
Ken-ichi Takayama et al.
Molecular endocrinology (Baltimore, Md.), 26(5), 748-761 (2012-03-30)
Despite the existence of effective antiandrogen therapy for prostate cancer, the disease often progresses to castration-resistant states. Elucidation of the molecular mechanisms underlying the resistance for androgen deprivation in terms of the androgen receptor (AR)-regulated pathways is a requisite to
TACC1-chTOG-Aurora A protein complex in breast cancer.
Conte, N; Delaval, B; Ginestier, C; Ferrand, A; Isnardon, D; Larroque, C; Prigent et al.
Oncogene null
T L Wong et al.
Journal of applied microbiology, 103(4), 803-810 (2007-09-28)
To survey the prevalence of Salmonella in imported and domestic pet chews for assessing their potential in introducing novel pathogenic and antimicrobial resistant Salmonella serotype clones into New Zealand, and as vehicles of salmonellosis in the domestic home environment. Three
M Myrmel et al.
Journal of fish diseases, 37(4), 349-355 (2013-04-27)
The aquaculture industry needs a simple, inexpensive and safe method for the treatment of fish waste without heat. Microbial inactivation by inorganic acid (HCl) or base (KOH) was determined using infectious pancreatic necrosis virus (IPNV) as a model organism for
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