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生物来源
rabbit
质量水平
抗体产品类型
primary antibodies
克隆
polyclonal
种属反应性
mouse, human
制造商/商品名称
Upstate®
技术
immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable
同位素/亚型
IgG
NCBI登记号
UniProt登记号
运输
dry ice
基因信息
human ... ARPC2(10109)
特异性
Recognizes p34-Arc/ARPC2 of the Arp2/3 complex.
免疫原
Peptide corresponding to amino acids 285-298 of human Arc
应用
Anti-p34-Arc/ARPC2 Antibody detects level of p34-Arc/ARPC2 & has been published & validated for use in IC, IH & WB.
Research Category
Cell Structure
Cell Structure
Research Sub Category
Cytoskeleton
Cytoskeleton
质量
routinely evaluated by immunoblot on RIPA lysates from human A431, Jurkat, and mouse 3T3 cells
目标描述
34 kDa
外形
Protein A purified
Format: Purified
Protein A Purified immunoglobulin in 0.07M Tris-glycine, pH 7.4, 0.105M NaCl, 0.035% sodium azide and 30% glycerol.
储存及稳定性
Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
分析说明
Control
Positive Control Included: Non-Stim A431 Cell Lysate (12-301)
Positive Control Included: Non-Stim A431 Cell Lysate (12-301)
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
The role of Arp2/3 in growth cone actin dynamics and guidance is substrate dependent.
The Journal of Neuroscience null
Organization of the Arp2/3 complex in hippocampal spines.
The Journal of Neuroscience null
Formation of adherens junctions leads to the emergence of a tissue-level tension in epithelial monolayers.
Journal of Cell Science null
Structural basis for regulation of Arp2/3 complex by GMF.
Nature Structural and Molecular Biology null
Oncotarget, 6(16), 14556-14571 (2015-05-27)
Here we have shown that β-cytoplasmic actin acts as a tumor suppressor, inhibiting cell growth and invasion in vitro and tumor growth in vivo. In contrast, γ-cytoplasmic actin increases the oncogenic potential via ERK1/2, p34-Arc, WAVE2, cofilin1, PP1 and other
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