07-2262
Anti-WNK3 Antibody
from rabbit, purified by affinity chromatography
别名:
WNK lysine deficient protein kinase 3, serine/threonine-protein kinase WNK3, Protein kinase with no lysine 3, Protein kinase lysine-deficient 3, protein kinase, lysine deficient 3
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所有图片(1)
About This Item
UNSPSC代码:
12352203
eCl@ss:
32160702
推荐产品
生物来源
rabbit
质量水平
抗体产品类型
primary antibodies
克隆
polyclonal
纯化方式
affinity chromatography
种属反应性
human, mouse
技术
western blot: suitable
NCBI登记号
UniProt登记号
运输
wet ice
靶向翻译后修饰
unmodified
基因信息
human ... WNK3(65267)
一般描述
WNK3 is a serine-threonine protein kinase and expressed throughout the nephron, but most commonly at intercellular junctions. In its active state, it is a promoter of NKCC2 and NCC activity. The opposite is true of WNK3 when in an inactive state. WNK3 changes the expression of these transporters in the membrane and is thought to be a regulator of blood pressure along with other members of the WNK family of protein kinases. In recent research, WNK3 has also been linked to regulating signaling cascades involved in tumorigenesis.
特异性
Other homologies: Rat (74% sequence homology).
免疫原
GST-tagged recombinant protein corresponding to human WNK3.
应用
Research Category
Signaling
Signaling
Research Sub Category
Developmental Signaling
Developmental Signaling
This WNK3 antibody is validated for use in WB for the detection of the WNK3 protein.
质量
Evaluated by Western Blot in HEK293 cell lysate.
Western Blot Analysis: 1:1,000 dilution of this antibody detected WNK3 on 10 µg of HEK293 cell lysate.
Western Blot Analysis: 1:1,000 dilution of this antibody detected WNK3 on 10 µg of HEK293 cell lysate.
目标描述
~220 kDa observed. Uncharacterized bands appear at ~52 and 60 kDa
外形
Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
储存及稳定性
Stable for 1 year at 2-8°C from date of receipt.
分析说明
Control
HEK293 cell lysate
HEK293 cell lysate
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
12 - Non Combustible Liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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