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Nanomedicine : nanotechnology, biology, and medicine, 10(1), 1-9 (2013-07-03)
Human biodistribution, bioprocessing and possible toxicity of nanoscale silver receive increasing health assessment. We prospectively studied commercial 10- and 32-ppm nanoscale silver particle solutions in a single-blind, controlled, cross-over, intent-to-treat, design. Healthy subjects (n=60) underwent metabolic, blood counts, urinalysis, sputum
Nature communications, 14(1), 3541-3541 (2023-06-16)
The RAC1-WAVE-Arp2/3 signaling pathway generates branched actin networks that power lamellipodium protrusion of migrating cells. Feedback is thought to control protrusion lifetime and migration persistence, but its molecular circuitry remains elusive. Here, we identify PPP2R1A by proteomics as a protein
ERK-MAPK drives lamellipodia protrusion by activating the WAVE2 regulatory complex.
Molecular Cell null
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 32(3), 1665-1676 (2017-11-23)
Podocyte malfunction is central to glomerular diseases and is marked by defective podocyte intercellular junctions and actin cytoskeletal dynamics. Podocytes share many morphologic features with neurons, so that similar sets of proteins appear to regulate cell process formation. One such
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