推荐产品
生物来源
rabbit
质量水平
抗体形式
purified antibody
抗体产品类型
primary antibodies
克隆
polyclonal
种属反应性
rat, mouse
制造商/商品名称
Upstate®
技术
immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
同位素/亚型
IgG
NCBI登记号
UniProt登记号
运输
wet ice
靶向翻译后修饰
unmodified
基因信息
human ... KALRN(8997)
特异性
Kalirin;不与Trio发生交叉反应
免疫原
GST融合蛋白,对应于大鼠Kalirin的517-976位残基,用凝血酶切割以去除GST部分;简称JH2582
应用
抗Trio抗体是针对Trio的抗体,可用于IP、WB & IC。
研究子类别
G蛋白
细胞骨架信号转导
G蛋白
细胞骨架信号转导
研究类别
信号传导
信号传导
质量
通过免疫印迹对来自大鼠脑微粒体蛋白制剂的RIPA裂解液进行常规评估;可能需要较长的暴露时间
目标描述
190、115、370和420kDa亚型
外形
0.1M Tris-甘氨酸(pH 7.4),0.15M NaCl,0.05%叠氮化钠,然后添加甘油至30%
形式:纯化
蛋白A层析
储存及稳定性
在-20°C下可保存2年
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
WGK
WGK 1
The Journal of biological chemistry, 274(5), 2929-2937 (1999-01-23)
The production and regulated secretion of bioactive peptides require a series of lumenal enzymes to convert inactive precursors into bioactive peptides plus several cytosolic proteins to govern granule formation, maturation, translocation, and exocytosis. Peptidylglycine alpha-amidating monooxygenase (PAM), an enzyme essential
Kalirin inhibition of inducible nitric-oxide synthase.
The Journal of Biological Chemistry, 274, 993-999 (1999)
The Journal of neuroscience : the official journal of the Society for Neuroscience, 32(34), 11864-11878 (2012-08-24)
Deficits in social and communication behaviors are common features of a number of neurodevelopmental disorders. However, the molecular and cellular substrates of these higher order brain functions are not well understood. Here we report that specific alterations in social and
Neurobiology of aging, 33(12), 2807-2816 (2012-03-21)
Psychosis in Alzheimer disease differentiates a subgroup with more rapid decline, is heritable, and aggregates within families, suggesting a distinct neurobiology. Evidence indicates that greater impairments of cerebral cortical synapses, particularly in dorsolateral prefrontal cortex, may contribute to the pathogenesis
The Rho-GEF Kalirin regulates bone mass and the function of osteoblasts and osteoclasts.
Bone null
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