07-102
Anti-IGF2BP1/2 Antibody
from rabbit, purified by affinity chromatography
别名:
Hepatocellular carcinoma autoantigen p62, IGF-II mRNA-binding protein 2, IGF2 mRNA-binding protein 2, VICKZ family member 2, insulin-like growth factor 2 mRNA binding protein 2
产品名称
Anti-IGF2BP1/2 Antibody, from rabbit, purified by affinity chromatography
biological source
rabbit
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
human
species reactivity (predicted by homology)
rat (based on 100% sequence homology)
technique(s)
immunoprecipitation (IP): suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
Quality Level
Gene Information
human ... IGF2BP1(10642), IGF2BP2(10644)
Analysis Note
Control
HEK293 cell lysate
HEK293 cell lysate
Evaluated by Western Blot in HEK293 cell lysate.
Western Blot Analysis: 0.1 µg/mL of this antibody detected IGF2BP1/2 on 10 µg of HEK293 cell lysate.
Western Blot Analysis: 0.1 µg/mL of this antibody detected IGF2BP1/2 on 10 µg of HEK293 cell lysate.
Application
Anti-IGF2BP1/2 Antibody is a Rabbit Polyclonal Antibody for detection of IGF2BP1/2 also known as Hepatocellular carcinoma autoantigen p62, IGF2 mRNA-binding protein 2 & has been validated in WB & IP.
Research Category
Apoptosis & Cancer
Apoptosis & Cancer
Research Sub Category
RNA Metabolism & Binding Proteins
RNA Metabolism & Binding Proteins
RNA Metabolism & Binding Proteins
RNA Metabolism & Binding Proteins
Western Blot (SNAP ID) Analysis: 4 µg/mL from a representative lot detected IGF2BP1/2 on 10 µg of HEK293 cell lysate.
Immunoprecipitation Analysis: 4 µg/mL from a representative lot was used by an independent laboratory in IP.
Immunoprecipitation Analysis: 4 µg/mL from a representative lot was used by an independent laboratory in IP.
Biochem/physiol Actions
This antibody recognizes IGF2BP1 and IGFBP2 at the C-terminus.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
Insulin-like growth factor 2 mRNA-binding proteins are RNA-binding factors belonging to the IMP (IGF-II mRNA-binding protein) family of proteins. These proteins contain four K homology domains and two RNA recognition motifs. IGF2BP′s have key roles in regulating the translation of target mRNAs. For the insulin-like growth factor 2 (IGF2) gene, IGF2BP′s bind to the 5′ UTR of the mRNA and regulate translation. IGF2BP′s are expressed in a variety of fetal tissues such as; follicles in ovary, liver, lung, kidney, thymus, placenta. Expression has also been observed in the gonoocytes of testis, oocytes, semen, spermatagonia and in several cancers including; testicular, lung, kidney, trachea, and prostate.
~63 kDa observed. Reactivity has been observed for both IGF2BP1 and IGF2BP2
Immunogen
Epitope: C-terminus
KLH-conjugated linear peptide corresponding to human IGF2BP1/2 at the C-terminus.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Physical form
Affinity purified
Purified rabbit polyclonal containing PBS with 0.09% azide.
Preparation Note
Stable for 1 year at 2-8°C from date of receipt.
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存储类别
10-13 - German Storage Class 10 to 13
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