推荐产品
生物来源
rabbit
质量水平
抗体形式
affinity purified immunoglobulin
抗体产品类型
primary antibodies
克隆
polyclonal
纯化方式
affinity chromatography
种属反应性
human, mouse, rat
制造商/商品名称
Upstate®
技术
western blot: suitable
同位素/亚型
IgG
NCBI登记号
UniProt登记号
运输
dry ice
靶向翻译后修饰
phosphorylation (pThr187)
基因信息
human ... CDKN1B(1027)
特异性
磷酸化Kip1
免疫原
对应于人Kip1氨基酸179-190的KLH偶联合成肽（C-PNAGSVEQ[pT]PKK）
应用
抗磷酸化-Kip1（Thr187）抗体是一种高质量的兔多克隆抗体，用于检测 磷酸化-Kip1（Thr187），&已在 WB 中验证。
研究子类别
细胞周期，DNA 复制&修复
细胞周期，DNA 复制&修复
研究类别
表观遗传学&核功能
表观遗传学&核功能
质量
通过免疫印迹法对HeLa 细胞RIPA裂解液进行了常规评估
目标描述
27kDa
外形
0.2M Tris、0.15M NaCl、0.1mM EDTA、0.05％叠氮化钠，然后添加甘油至30％
免疫亲和层析
储存及稳定性
在-20°C下保存1年
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
WGK
WGK 1
p27KIP1, an inhibitor of cyclin-dependent kinases.
Koff, A and Polyak, K
Progress in Cell Cycle Research, 1, 141-147 (1995)
Oncostatin M induces growth arrest by inhibition of Skp2, Cks1, and cyclin A expression and induced p21 expression.
Halfter, H; Friedrich, M; Resch, A; Kullmann, M; Stogbauer, F; Ringelstein, EB; Hengst, L
Cancer Research null
G Wolf
Kidney international, 56(4), 1262-1265 (1999-10-03)
There are two fundamentally different growth responses for cells comprising the nephron: hyperplasia or hypertrophy. Cells that progress through the normal cell cycle double their DNA content and eventually divide during mitosis. Those cells that hypertrophy stop the growth process
J Kato
Frontiers in bioscience : a journal and virtual library, 4, D787-D792 (1999-11-30)
The first gap phase (G1) in the mammalian cell cycle plays a pivotal role in determining whether or not cells are to initiate DNA replication. Progression through G1 phase and transition into S phase are positively and negatively regulated by
Shuichan Xu et al.
The Journal of biological chemistry, 282(21), 15462-15470 (2007-04-06)
p27, an important cell cycle regulator, blocks the G(1)/S transition in cells by binding and inhibiting Cdk2/cyclin A and Cdk2/cyclin E complexes (Cdk2/E). Ubiquitination and subsequent degradation play a critical role in regulating the levels of p27 during cell cycle
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