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Merck
CN
所有图片(1)

文件

06-903

Sigma-Aldrich

PKA抗体,NT

Upstate®, from rabbit

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About This Item

UNSPSC代码:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物来源

rabbit

质量水平

抗体形式

purified antibody

抗体产品类型

primary antibodies

克隆

polyclonal

种属反应性

hamster, bovine, rat, pig, mouse, human

制造商/商品名称

Upstate®

技术

western blot: suitable

同位素/亚型

IgG

NCBI登记号

UniProt登记号

运输

wet ice

靶向翻译后修饰

unmodified

基因信息

human ... TYRO3(7301)

特异性

PKA,PKA重组人α同工型

免疫原

基于PKA催化亚基的人41kDaα同工型氨基酸8-22的肽(KKGSEQESVKEFLAK-C)

应用

抗PDGF中和抗体,可检测PDGF的水平&已有相关文献发布 & 通过蛋白质印迹验证。
研究子类别
细胞骨架信号转导
研究类别
信号传导

质量

通过免疫印迹法对大鼠脑微粒体制备物或PC-12 RIPA细胞裂解液进行了常规评估

目标描述

41kDa

外形

0.1M Tris-甘氨酸,pH 7.4,0.15M NaCl,0.05%叠氮化钠,然后添加甘油至30%
形式:纯化
蛋白A层析

储存及稳定性

在-20°C下可保存2年

法律信息

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

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Zhaoqing Zheng et al.
Journal of neurophysiology, 101(5), 2539-2549 (2009-03-06)
The cyclic AMP-dependent protein kinase (PKA) signaling pathway has been shown to be important in mechanisms of synaptic plasticity, although its direct and downstream signaling effects are not well understood. Using an in vitro model of eyeblink classical conditioning, we
Ho-Lin Chuang et al.
Environmental toxicology, 36(9), 1873-1879 (2021-06-06)
Epimedium, is used traditionally in Chinese medicine to treat infertility problems. In this study, we establish the cell model to elucidate the protective effect of epimedium against ES by analyzing the molecular relationship between mitochondrial dynamics and steroidogenesis and to
The Chinese herbal medicine Dai-Zong-Fang promotes browning of white adipocytes in vivo and in vitro by activating PKA pathway to ameliorate obesity.
Xu, et al.
Frontiers in Pharmacology, 14, 1176443-1176443 (2023)
Wanxu Guo et al.
Biology open, 10(5) (2020-10-14)
Podocytes are the major target in proteinuric kidney diseases such as diabetic nephropathy. The underlying molecular mechanisms by which high glucose (HG) results in podocyte damage remain unclear. This study investigated the regulatory role of Smad3, ezrin, and protein kinase
Gregory Segala et al.
Nature communications, 10(1), 1833-1833 (2019-04-25)
In response to extracellular signals, many signalling proteins associated with the plasma membrane are sorted into endosomes. This involves endosomal fusion, which depends on the complexes HOPS and CORVET. Whether and how their subunits themselves modulate signal transduction is unknown.

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