推荐产品
生物来源
rabbit
质量水平
抗体形式
serum
抗体产品类型
primary antibodies
克隆
polyclonal
种属反应性
rat, human, mouse
制造商/商品名称
Upstate®
技术
western blot: suitable
同位素/亚型
IgG
NCBI登记号
UniProt登记号
运输
dry ice
靶向翻译后修饰
phosphorylation (pSer726)
基因信息
human ... STAT5A(6776)
特异性
phosphorylated STAT5A (S726) and STAT5B (S731), does not recognize STAT5B containing a S731A mutation
免疫原
peptide (DQAP[pS]PAVC) corresponding to amino acids 722-730 of human STAT5A or 727-735 of human STAT5B
应用
Anti-phospho-STAT5A/B (Ser726/Ser731) Antibody is a rabbit polyclonal antibody for detection of phospho-STAT5A/B (Ser726/Ser731) also known as signal transducer & activator of transcription 5A/B & has been tested in WB.
Research Category
Epigenetics & Nuclear Function
Epigenetics & Nuclear Function
Research Sub Category
Transcription Factors
Transcription Factors
质量
routinely evaluated by immunoprecipitating STAT5A from RIPA lysates of Nb2-Sp cells that had been treated with prolactin; subsequent immunoblotting was performed using Anti-STAT5A (Catalog #06-968)
目标描述
94kDa
外形
Antiserum
rabbit antiserum in 30% glycerol and 0.05% sodium azide
储存及稳定性
2 years at -20°C
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
12 - Non Combustible Liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Development of pure prolactin receptor antagonists.
Bernichtein, S; Kayser, C; Dillner, K; Moulin, S; Kopchick, JJ; Martial, JA; Norstedt et al.
The Journal of Biological Chemistry null
P L Bergad et al.
The Journal of biological chemistry, 275(11), 8114-8120 (2000-03-14)
A growth hormone-inducible nuclear factor complex (GHINF), affinity-purified using the growth hormone response element (GHRE) from the promoter of rat serine protease inhibitor 2.1, was found to contain Stat5a and -5b, as well as additional components. The ubiquitous transcription factor
Two discrete regions of interleukin-2 (IL2) receptor beta independently mediate IL2 activation of a PD98059/rapamycin/wortmannin-insensitive Stat5a/b serine kinase.
Kirken, R A, et al.
The Journal of Biological Chemistry, 272, 15459-15465 (1997)
R A Kirken et al.
The Journal of biological chemistry, 272(22), 14098-14103 (1997-05-30)
Transcription factors of the Stat gene family are selectively activated by many hormones and cytokines. Stat5 originally was cloned as a prolactin-stimulated DNA-binding protein, but is also activated by non-lactogenic cytokines in many cell types. The recent identification of two
H Yamashita et al.
The Journal of biological chemistry, 273(46), 30218-30224 (1998-11-07)
Transcription factors of the Stat family are controlled by protein kinases. Phosphorylation of a positionally conserved tyrosine residue is obligatory for Stat dimerization, nuclear translocation, and specific DNA binding. Studies of Stat1 and Stat3 have suggested that serine phosphorylation may
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