06-570-AF488
抗磷酸组蛋白H3(Ser10)抗体，Alexa Fluor™ 488偶联物
from rabbit, ALEXA FLUOR™ 488
别名:
H3S10P, Histone H3 (phospho Ser10), H3 histone, family 3A, H3.3A, H3 histone, family 3B, H3.3B
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选择尺寸
关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
ALEXA FLUOR™ 488
Clone:
polyclonal
Application:
ICC
Citations:
12
biological source
rabbit
conjugate
ALEXA FLUOR™ 488
antibody form
purified antibody
antibody product type
primary antibodies
clone
polyclonal
species reactivity
human, mouse
technique(s)
immunocytochemistry: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
phosphorylation (pSer10)
Quality Level
Gene Information
human ... HIST1H3F(8968)
General description
组蛋白H3是参与真核细胞染色质结构的五种主要组蛋白之一。H3具有一个主要的球状结构域和一个长N末端的尾巴，其与核糖体核小体′串珠′结构体的结构有关。组蛋白H3的N末端尾部从球状核小体核心突起，其可能发生几种不同类型的表观遗传修饰，从而影响细胞过程。这些修饰包括甲基或乙酰基与赖氨酸和精氨酸的共价连接，以及丝氨酸或苏氨酸的磷酸化。
可观察到约17 kDa的条带
Immunogen
对应于磷酸化组蛋白H3(Ser10)的线性肽。
Application
免疫细胞化学分析：代表性批次的1:50稀释液可在NIH/3T3细胞中检测到磷酸化组蛋白H3 (Ser10)。
蛋白质印迹分析：代表性批次的1：1,000稀释液可在HeLa细胞中检测到组蛋白H3 (Ser10)。
蛋白质印迹分析：代表性批次的1：1,000稀释液可在HeLa细胞中检测到组蛋白H3 (Ser10)。
抗磷酸化H3 (Ser10)抗体-Alexa Fluor™ 488偶联物是一种纯化的兔多克隆抗体，可检测丝氨酸 10 磷酸化的组蛋白 H3。该抗体采用Alexa Fluor 488标记，并通过IC验证。该抗体的无标记版本得到广泛引用，并通过ICC、I IP & WB验证。
研究子类别
表位标签
表位标签
研究类别
表位标签 & 一般用途
表位标签 & 一般用途
Physical form
纯化的兔抗体偶联物，溶于含有PBS、15 mg BSA和0.1%叠氮化钠的缓冲液中。
纯化蛋白A
Preparation Note
自收到之日起，在2-8°C条件下可稳定保存1年。
Analysis Note
通过免疫细胞化学在HeLa细胞中进行评估。
免疫细胞化学分析：用该抗体的1:50稀释液可在HeLa细胞中检测磷酸化组蛋白H3 (Ser10)。
Alexa Fluor™是Life Technologies的注册商标。
免疫细胞化学分析：用该抗体的1:50稀释液可在HeLa细胞中检测磷酸化组蛋白H3 (Ser10)。
Alexa Fluor™是Life Technologies的注册商标。
Other Notes
浓度：请参考批次特异性浓缩物的检验报告。
Legal Information
ALEXA FLUOR is a trademark of Life Technologies
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Baiping Cui et al.
Cell regeneration (London, England), 11(1), 9-9 (2022-04-02)
Myocardial regeneration has been considered a promising option for the treatment of adult myocardial injuries. Previously, a chick early amniotic fluid (ceAF) preparation was shown to contain growth-related factors that promoted embryonic growth and cellular proliferation, though the nature of
Edward E Large et al.
PLoS genetics, 13(5), e1006769-e1006769 (2017-05-12)
Most biological traits and common diseases have a strong but complex genetic basis, controlled by large numbers of genetic variants with small contributions to a trait or disease risk. The effect-size of most genetic variants is not absolute and is
Xinlu Gao et al.
International journal of medical sciences, 19(8), 1254-1264 (2022-08-06)
Mammalian cardiomyocytes (CMs) maintain a low capacity for self-renewal in adulthood, therefore the induction of CMs cycle re-entry is an important approach to promote myocardial repair after injury. Recently, photobiomodulation (PBM) has been used to manipulate physiological activities of various
Erin J Vanzyl et al.
PloS one, 13(1), e0191178-e0191178 (2018-01-18)
The spliceosome is a large ribonucleoprotein complex that catalyzes the removal of introns from RNA polymerase II-transcribed RNAs. Spliceosome assembly occurs in a stepwise manner through specific intermediates referred to as pre-spliceosome complexes E, A, B, B* and C. It
Gaetana Gambino et al.
PloS one, 17(12), e0278966-e0278966 (2022-12-13)
Microtubule-associated 1B (MAP1B) proteins are expressed at the nervous system level where they control cytoskeleton activity and regulate neurotransmitter release. Here, we report about the identification of a planarian MAP1B factor (DjMap1B) that is enriched in cephalic ganglia and longitudinal
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