06-520
抗-Na+/K+ ATPase α-1抗体
Upstate®, from rabbit
别名:
Anti-CMT2DD
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
immunocytochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Species reactivity:
bovine, rat, human
Citations:
44
Technique(s):
immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
immunoprecipitation (IP): suitable
western blot: suitable
Uniprot accession no.:
产品名称
抗-Na+/K+ ATPase α-1抗体, Upstate®, from rabbit
biological source
rabbit
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
clone
polyclonal
species reactivity
bovine, rat, human
packaging
antibody small pack of 25 μg
manufacturer/tradename
Upstate®
technique(s)
immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
ambient
target post-translational modification
unmodified
Quality Level
Gene Information
rat ... Atp1A1(24211)
Analysis Note
对照
大鼠脑微粒体制备溶解物。
大鼠脑微粒体制备溶解物。
通过免疫沉淀对大鼠脑微粒体制备溶解物进行常规评估
Application
研究子类别
离子通道&转运子
离子通道&转运子
研究类别
神经科学
神经科学
该抗 Na+/K+ ATPase α-1 抗体经过验证可用在IC、IP、WB 中检测 Na+/K+ ATPase α-1。
Biochem/physiol Actions
识别 Na+/K+ ATPase 的 α-1 亚基亚型。
预期与大鼠（100％），小鼠（99％）；人，猪，兔，猴（96％）发生交叉反应。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
112kda
Na+/K+ ATPase α-1 是人基因，可在整个细胞膜上维持 Na+ 和 K+，这对于渗透调节非常重要。它是（Na+/K+）ATPase 的组成部分，ATPase 是一种催化 ATP 水解并在质膜上运输钠离子和钾离子的转运蛋白。它还与 Src 和其他信号蛋白结合。哇巴因和其他强心类固醇与（Na+/K+）ATPase 的结合会激活 Src，从而导致多个信号级联的组装和激活。哇巴因的结合也诱导正肌力作用。 甲状腺毒性周期性麻痹和甲状腺功能亢进是与 ATPase 相关的疾病。（参考：维基百科和 http://www.bioportfolio.com/gene/476-ATP1A1.html）
Immunogen
具有 GST 标签的 ATPase。
表位：细胞质结构域
Other Notes
浓度：请参考批次特异性浓缩物的分析证书。
Physical form
在含有 0.1M Tris- 甘氨酸（pH7.4）150mM NaCl 和 0.05％ NaN3 的缓冲液中的纯化抗体。
形式：纯化的
纯化的蛋白 A
Preparation Note
自收到之日起，在 2-8ºC 条下可稳定保存 1 年。
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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