推荐产品
生物来源
rabbit
质量水平
抗体形式
serum
克隆
polyclonal
种属反应性
mouse, human
制造商/商品名称
Upstate®
技术
immunoprecipitation (IP): suitable
western blot: suitable
同位素/亚型
IgG
NCBI登记号
UniProt登记号
运输
dry ice
靶向翻译后修饰
unmodified
基因信息
human ... GNB2(2783)
特异性
Gβ subunits; recognizes both isoforms
免疫原
Internal sequence of G-protein β subunit (KTREGNVRVSREL) conjugated to octavalent polylysine base
应用
Detect Gβ using this Anti-Gβ Antibody validated for use in IP & WB.
质量
Immunoblot Analysis: A 1:500-1:1000 dilution of this antibody detected the Gβ subunits in 20 μg of a cell lysate prepared from rat brain microsomal preparation (Catalog # 12-144).
Immunoprecipitation/Immunoblot: 10 μl of this antibody immunoprecipitated the Gβ subunit from 500 μg-1mg of a lysate of rat brain microsomal preparation (Catalog # 12-144).
Immunoprecipitation/Immunoblot: 10 μl of this antibody immunoprecipitated the Gβ subunit from 500 μg-1mg of a lysate of rat brain microsomal preparation (Catalog # 12-144).
目标描述
35/36kDa
外形
PBS, pH 7.2
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
储存分类代码
10 - Combustible liquids
WGK
WGK 2
J Yamauchi et al.
The Journal of biological chemistry, 272(12), 7602-7607 (1997-03-21)
G protein beta and gamma subunits (Gbeta and Ggamma) form a complex that is involved in various signaling pathways. We reported that the C-terminal 10 amino acids of Gbeta are required for association with Ggamma (Yamauchi, J., Kaziro, Y., and
Activation of p38 mitogen-activated protein kinase (p38 MAPK), extracellular signal-regulated kinase (ERK) and c-jun N-terminal kinase (JNK) during hypoxia in cerebral cortical nuclei of guinea pig fetus at term: role of nitric oxide.
Dev Maulik, Qazi M Ashraf, Om P Mishra, Maria Delivoria-Papadopoulos
Neuroscience Letters null
J Yamauchi et al.
The Journal of biological chemistry, 274(4), 1957-1965 (1999-01-16)
Heterotrimeric G protein beta gamma subunit (Gbeta gamma) mediates signals to two types of stress-activated protein kinases, c-Jun NH2-terminal kinase (JNK) and p38 mitogen-activated protein kinase, in mammalian cells. To investigate the signaling mechanism whereby Gbeta gamma regulates the activity
J Yamauchi et al.
The Journal of biological chemistry, 272(44), 27771-27777 (1997-11-05)
Various extracellular stimuli activate three classes of mitogen-activated protein kinases (MAPKs): extracellular signal-regulated kinase, c-Jun N-terminal kinase, and p38 MAPK. In mammalian cells, p38 MAPK is activated by endotoxins, inflammatory cytokines, and environmental stresses. We show here that p38 MAPK
J Yamauchi et al.
The Journal of biological chemistry, 275(11), 7633-7640 (2000-03-14)
Heterotrimeric G proteins stimulate the activities of two stress-activated protein kinases, c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein kinase in mammalian cells. In this study, we examined whether alpha subunits of G(i) family activate JNK using transient expression system
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