推荐产品
生物来源
rabbit
质量水平
抗体形式
purified antibody
抗体产品类型
primary antibodies
克隆
polyclonal
种属反应性
mouse, human, rat, bovine
制造商/商品名称
Upstate®
技术
immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
同位素/亚型
IgG
NCBI登记号
UniProt登记号
运输
wet ice
靶向翻译后修饰
unmodified
基因信息
human ... GNAI1(2770)
特异性
可识别Giα1和Giα2。
免疫原
10个残基的合成肽（KNNLKDCGLF），对应于Gia1和Gia2的C端
应用
可使用这种经验证可用于IC、IP & WB的Giα1/2抗体检测Giα1/2。
研究子类别
GPCR, cAMP/cGMP & 钙信号传导
GPCR, cAMP/cGMP & 钙信号传导
研究类别
信号传导
信号传导
质量
通过免疫印迹法对大鼠脑微粒体制备物或小鼠3T3/A31成纤维细胞的溶解质膜进行了常规评估
目标描述
40 kDa
外形
PBS（50 mM KHPO4、140 mM NaCl）稀释的兔血清。冷冻溶液
形式：纯化
储存及稳定性
自收到之日起在-20°C可稳定保存2年。避免反复冻融。为了最大程度地回收产品，在融化后和取下盖子之前，将原始小瓶进行离心。
分析说明
对照
广泛表达
广泛表达
其他说明
浓度：请参考批次特异性浓缩物的检验报告。
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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储存分类代码
10 - Combustible liquids
WGK
WGK 1
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During antidiuresis, increases in vasopressin (AVP)-elicited osmotic water permeability in the terminal inner medullary collecting duct (tIMCD) raise luminal calcium concentrations to levels (> or = 5 mM) above those associated with the formation of calcium-containing precipitates in the urine.
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Adenylate cyclase in liver plasma membranes from streptozotocin-diabetic (STZ) or BB/Wor spontaneously diabetic rats showed increased responsiveness to GTP, glucagon, fluoroaluminate, and cholera toxin. Basal or forskolin-stimulated activity was unchanged in STZ rats, but increased in BB/Wor rats. No change
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FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 14(11), 1619-1628 (2000-08-06)
Mimicking short photoperiod melatonin signals (16 h exposure) on primary cell cultures of melatonin target cells of the ovine pars tuberalis (PT) results in an enhanced cAMP response to forskolin stimulation relative to untreated cells, a phenomenon termed sensitization. The
Disulfide bonds in the extracellular calcium-polyvalent cation-sensing receptor correlate with dimer formation and its response to divalent cations in vitro
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The Journal of Biological Chemistry, 273, 14476-14483 (1998)
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Oncogene, 37(6), 756-767 (2017-10-24)
B-cell chronic lymphocytic leukemia (B-CLL) cells are resistant to apoptosis, and consequently accumulate to the detriment of normal B cells and patient immunity. Because current therapies fail to eradicate these apoptosis-resistant cells, it is essential to identify alternative survival pathways
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