生物来源
rabbit
质量水平
抗体形式
purified antibody
抗体产品类型
primary antibodies
克隆
polyclonal
种属反应性
human, mouse, rat
技术
western blot: suitable
NCBI登记号
UniProt登记号
运输
wet ice
靶向翻译后修饰
unmodified
基因信息
human ... SRSF4(6429)
一般描述
SRp75, also known as Serine/arginine-rich splicing factor 4, is an essential splicing factor that is a member of the SR family of proteins. This protein is a component of the pre-mRNA splicing complex and is believed to play a role in alternative splice site selection. Consistent with this excess levels of SRp75 have been shown to play a role in alternative splicing of CD45. SRp75 is normally found in the nucleus and is known to be hyperphosphorylated at serine residues in its RS domain.
免疫原
KLH-conjugated linear peptide corresponding to human SRp75.
应用
Anti-SRp75 Antibody is a rabbit polyclonal antibody for detection of SRp75 also known as serine/arginine-rich splicing factor 4, SR splicing factor 4, Pre-mRNA-splicing factor SRP75 & has been validated in WB.
Immunoprecipitation Analysis: A reprentative lot of this antibody was used by an independent laboratory in IP. (Jiang, K., et al. (2009). Endocrinology. 150(5):2087-2097.)
质量
Evaluated by Western Blot in L6 cell lysate.
Western Blot Analysis: 1:500 dilution of this antibody detected SRp75 on 10 µg of L6 cell lysate.
Western Blot Analysis: 1:500 dilution of this antibody detected SRp75 on 10 µg of L6 cell lysate.
目标描述
~ 62 kDa observed
外形
Format: Purified
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储存分类代码
12 - Non Combustible Liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Stretching muscle cells induces transcriptional and splicing transitions and changes in SR proteins.
Hinkle, et al.
Communications biology, 5, 987-987 (2022)
Paul L Boutz et al.
Genes & development, 29(1), 63-80 (2015-01-07)
Deep sequencing of embryonic stem cell RNA revealed many specific internal introns that are significantly more abundant than the other introns within polyadenylated transcripts; we classified these as "detained" introns (DIs). We identified thousands of DIs, many of which are
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