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Merck
CN
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文件

06-1091

Sigma-Aldrich

Anti-IL-13 receptor Antibody, alpha-2 (IL-13RA2)

from rabbit, purified by affinity chromatography

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别名:
interleukin 13 receptor, alpha 2, interleukin-13 receptor subunit alpha-2, interleukin 13 receptor alpha 2 chain, Interleukin-13-binding protein, IL-13R subunit alpha-2, cancer/testis antigen 19, IL-13 receptor subunit alpha-2, interleukin 13 binding pro
UNSPSC代码:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物来源

rabbit

质量水平

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

纯化方式

affinity chromatography

种属反应性

human

技术

immunohistochemistry: suitable (paraffin)
western blot: suitable

NCBI登记号

UniProt登记号

运输

wet ice

靶向翻译后修饰

unmodified

基因信息

human ... IL13RA2(3598)

一般描述

Interleukin-13 receptor subunit alpha-2 (IL-13RA2) is one receptor of Interleukin-13 which is a key moderator of asthma and allergic inflammation. IL-13 and its receptors have been shown to play a part in alcohol-mediated activation of pro-fibrotic pathways. IL-13 has a suppressive effect on macrophage activation but cannot activate T cells.

特异性

This antibody recognizes Interleukin-13 receptor, alpha-2 at the cytoplasmic domain.

免疫原

Epitope: Cytoplasmic Domain
KLH-conjugated linear peptide corresponding to human Interleukin-13 receptor, alpha-2 at the cytoplasmic domain.

应用

Anti-IL-13 receptor Antibody, alpha-2 (IL-13RA2) is an antibody against IL-13 receptor for use in WB, IH(P).
Research Category
Inflammation & Immunology
Research Sub Category
Cytokines & Cytokine Receptors
Western Blot (SNAP i.d. Protein Detection System) Analysis: 5 µg/mL from a previous lot detected Interleukin-13 receptor, alpha-2 in 10 µg of HeLa cell lysate.

Immunohistochemistry (paraffin) Analysis: A 1:500 dilution from a previous lot was used to detect Interleukin-13 receptor, alpha-2 in colorectal carcinoma and normal human kidney/medulla tissue sections.

质量

Evaluated by Western Blot in HeLa cell lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected Interleukin-13 receptor, alpha-2 in 10 µg of HeLa cell lysate.

目标描述

~44 kDa observed

外形

Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

分析说明

Control
HeLa cell lysate

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Yang Zhou et al.
The Journal of clinical investigation, 125(8), 3178-3192 (2015-06-30)
Hermansky-Pudlak syndrome (HPS) comprises a group of inherited disorders caused by mutations that alter the function of lysosome-related organelles. Pulmonary fibrosis is the major cause of morbidity and mortality in patients with subtypes HPS-1 and HPS-4, which both result from

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