推荐产品
生物来源
mouse
质量水平
抗体形式
culture supernatant
抗体产品类型
primary antibodies
克隆
C305, monoclonal
种属反应性
human
制造商/商品名称
Upstate®
技术
immunoprecipitation (IP): suitable
multiplexing: suitable
同位素/亚型
IgM
UniProt登记号
运输
dry ice
靶向翻译后修饰
unmodified
基因信息
human ... TRDD3(28523)
特异性
Jurkat T细胞受体
免疫原
Jurkat T细胞
应用
抗-T细胞受体抗体（克隆C305）可检测T细胞受体的水平 &已有相关文献发表&经过验证可用于Mplex & IP。
研究子类别
免疫球蛋白 & 免疫学
免疫球蛋白 & 免疫学
研究类别
炎症 & 免疫学
炎症 & 免疫学
质量
常规用于生物测定，用于激活Jurkat细胞中的T细胞受体信号级联
外形
浓缩的培养上清液。
储存及稳定性
自运送之日起在-20°C下稳定保存2年
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Monica L Friedrich et al.
The Journal of biological chemistry, 282(7), 4573-4584 (2006-12-22)
Death-associated protein-related apoptotic kinase-2 (DRAK2), a member of the death-associated protein-like family of serine/threonine kinases, is highly expressed in lymphoid organs and is a negative regulator of T cell activation. To investigate the regulation of DRAK2 activity in primary lymphocytes
Joseph Lin et al.
The Journal of cell biology, 162(4), 673-682 (2003-08-13)
CD148 is a receptor-like protein tyrosine phosphatase up-regulated on T cells after T cell receptor (TCR) stimulation. To examine the physiologic role of CD148 in TCR signaling, we used an inducible CD148-expressing Jurkat T cell clone. Expression of CD148 inhibits
A Weiss et al.
The Journal of experimental medicine, 160(5), 1284-1299 (1984-11-01)
The association between T3 and the T cell antigen receptor was examined using the T3 bearing T cell leukemic line Jurkat. A monoclonal antibody, C305, was produced, which reacted with idiotypic-like determinants expressed on Jurkat. The molecule with which this
Identification of the minimal tyrosine residues required for linker for activation of T cell function.
Lin, J and Weiss, A
The Journal of Biological Chemistry, 276, 29588-29595 (2001)
Pussadee Paensuwan et al.
Journal of immunology (Baltimore, Md. : 1950), 196(1), 448-458 (2015-11-22)
Ligand binding to the TCR causes a conformational change at the CD3 subunits to expose the CD3ε cytoplasmic proline-rich sequence (PRS). It was suggested that the PRS is important for TCR signaling and T cell activation. It has been shown
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