biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
ascites fluid
antibody product type
primary antibodies
clone
6A9, monoclonal
species reactivity
human
manufacturer/tradename
Upstate®
technique(s)
immunocytochemistry: suitable, immunoprecipitation (IP): suitable, western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... CDH3(1001)
General description
Mr 120kDa
Immunogen
P-Cadherin extracellular domain purified from A431 cell membranes.
Application
This Anti-P-Cadherin Antibody, clone 6A9 is validated for use in IP, WB, IC for the detection of P-Cadherin.
Biochem/physiol Actions
Recognizes P-Cadherin
Analysis Note
Control
Positive Antigen Control: Catalog #12-301, non-stimulated A431 cell lysate. Add 2.5µL of 2-mercaptoethanol/100µL of lysate and boil for 5 minutes to reduce the preparation. Load 20µg of reduced lysate per lane for minigels.
Positive Antigen Control: Catalog #12-301, non-stimulated A431 cell lysate. Add 2.5µL of 2-mercaptoethanol/100µL of lysate and boil for 5 minutes to reduce the preparation. Load 20µg of reduced lysate per lane for minigels.
Routinely evaluated by immunoblot on A431 cell lysates.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
10 - Combustible liquids
wgk
WGK 1
Cadherin function is required for human keratinocytes to assemble desmosomes and stratify in response to calcium
Lewis, J. E., et al
The Journal of Investigative Dermatology, 102, 870-877 (1994)
M D Hines et al.
Journal of cell science, 112 ( Pt 24), 4569-4579 (1999-11-27)
Cadherin function is required for normal keratinocyte intercellular adhesion and stratification. In the present study, we have investigated whether cadherin-cadherin interactions may also modulate keratinocyte differentiation, as evidenced by alterations in the levels of several differentiation markers. Confluent keratinocyte cultures
Differential displacement of classical cadherins by VE-cadherin
Jaggi, M., et al
Cell communication & adhesion, 9, 103-115 (2002)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 05-916 | 04053252279690 |