推荐产品
生物来源
mouse
质量水平
抗体形式
purified immunoglobulin
抗体产品类型
primary antibodies
克隆
5c10, monoclonal
种属反应性
mouse, rat, human
制造商/商品名称
Upstate®
技术
immunocytochemistry: suitable
western blot: suitable
同位素/亚型
IgG
NCBI登记号
UniProt登记号
运输
wet ice
靶向翻译后修饰
unmodified
基因信息
human ... STK11(6794)
特异性
Recognizes LKB1.
免疫原
GST fusion protein corresponding to residues 1-433 of human LKB1
应用
Research Category
Signaling
Signaling
Research Sub Category
Insulin/Energy Signaling
Insulin/Energy Signaling
This Anti-LKB1 Antibody, clone 5c10 is validated for use in IC, WB for the detection of LKB1.
质量
routinely evaluated by immunoblot on RIPA lysates from Rat2 cells
目标描述
55 kDa
外形
Protein G Purified
Format: Purified
Protein G Purified immunoglobulin in 0.1M Tris-Glycine, 0.15M NaCl and 0.05% Sodium Azide, pH 7.4.
储存及稳定性
Stable for 1 year at 2-8°C from date of receipt.
分析说明
Control
Rat2 cell lysate
Rat2 cell lysate
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
12 - Non Combustible Liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Yuji Nakada et al.
PloS one, 8(9), e73449-e73449 (2013-10-03)
Germline mutations in the LKB1 gene (also known as STK11) cause the Peutz-Jeghers Syndrome, and somatic loss of LKB1 has emerged as causal event in a wide range of human malignancies, including melanoma, lung cancer, and cervical cancer. The LKB1
Naoyuki Asada et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 30(26), 8852-8865 (2010-07-02)
Neuronal migration is an essential process for the development of the cerebral cortex. We have previously shown that LKB1, an evolutionally conserved polarity kinase, plays a critical role in neuronal migration in the developing neocortex. Here we show that LKB1
A F Baas et al.
The EMBO journal, 22(12), 3062-3072 (2003-06-14)
The LKB1 gene encodes a serine/threonine kinase mutated in Peutz-Jeghers cancer syndrome. Despite several proposed models for LKB1 function in development and in tumour suppression, the detailed molecular action of LKB1 remains undefined. Here, we report the identification and characterization
Molecular diagnosis and clinical relevance of t(9;22), t(4;11) and t(1 ;19) chromosome abnormalities in a consecutive group of 141 adult patients with acute lymphoblastic leukemia
Rambaldi, A., et al
Leukemia & Lymphoma, 21, 457-466 (1996)
Samantha M Behunin et al.
Archives of biochemistry and biophysics, 601, 32-41 (2016-03-15)
Contractile perturbations downstream of Ca(2+) binding to troponin C, the so-called sarcomere-controlled mechanisms, represent the earliest indicators of energy remodeling in the diseased heart [1]. Central to cellular energy "sensing" is the adenosine monophosphate-activated kinase (AMPK) pathway, which is known
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