推荐产品
生物来源
mouse
抗体形式
purified antibody
抗体产品类型
primary antibodies
克隆
FIGR, monoclonal
种属反应性
hamster, mouse, rat
请勿与下列物质发生反应
human
制造商/商品名称
Upstate®
技术
immunoprecipitation (IP): suitable
western blot: suitable
同位素/亚型
IgG2b
NCBI登记号
UniProt登记号
运输
dry ice
靶向翻译后修饰
unmodified
基因信息
human ... NR3C1(2908)
特异性
glucocorticoid receptor
免疫原
Native glucocorticoid receptor purified from rat liver
应用
Detect Glucocorticoid Receptor with Anti-Glucocorticoid Receptor Antibody, clone FIGR (Mouse Monoclonal Antibody), that has been shown to work in IP & WB.
Research Category
Epigenetics & Nuclear Function
Epigenetics & Nuclear Function
Research Sub Category
Transcription Factors
Transcription Factors
质量
routinely evaluated by immunoblot on RIPA lysates from L6, PC12, and 3T3/A31 cells.
目标描述
85-100kDa
外形
Protein G Purified
0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
Format: Purified
储存及稳定性
2 years at -20°C
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
WGK 1
J E Bodwell et al.
The Journal of biological chemistry, 266(12), 7549-7555 (1991-04-25)
Glucocorticoid receptors in vivo are phosphorylated in the absence of hormone and become hyperphosphorylated in the presence of glucocorticoid agonist but not antagonists (Ortí, E., Mendel, D.B., Smith, L.I., and Munck, A. (1989) J. Biol. Chem. 264, 9728-9731). As a
J Richardson et al.
Molecular endocrinology (Baltimore, Md.), 13(4), 546-554 (1999-04-09)
The glutamate synthetase gene (GS) contains a composite glucocorticoid response element (cGRE) comprised of a GRE and an adjacent element with features of both a cAMP-response element (CRE) and a 12-O-tetradecanoylphorbol 13-acetate (TPA) response element (TRE). The CRE/TRE element of
Arman Nayebosadri et al.
American journal of physiology. Cell physiology, 305(3), C309-C322 (2013-05-25)
The lamina serves to maintain the nuclear structure and stiffness while acting as a scaffold for heterochromatin and many transcriptional proteins. Its role in endothelial mechanotransduction, specifically how nuclear mechanics impact gene regulation under shear stress, is not fully understood.
R C Kaltreider et al.
Environmental health perspectives, 109(3), 245-251 (2001-05-03)
Chronic human exposure to nonovertly toxic doses of arsenic is associated with an increased risk of cancer. Although its carcinogenic mechanism is still unknown, arsenic does not directly cause DNA damage or mutations and is therefore thought to act principally
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