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生物来源
rabbit
质量水平
抗体形式
purified antibody
抗体产品类型
primary antibodies
克隆
monoclonal
种属反应性
human
制造商/商品名称
Upstate®
技术
inhibition assay: suitable (peptide)
multiplexing: suitable
western blot: suitable
同位素/亚型
IgG
NCBI登记号
UniProt登记号
运输
wet ice
靶向翻译后修饰
phosphorylation (pSer10), trimethylation (Lys9)
基因信息
human ... H3C1(8350)
特异性
Broad species cross-reactivity is expected
trimethyl (Lys9)-phospho (Ser10)-histone H3
免疫原
KLH-conjugated, synthetic peptide containing the sequenc...ARme3KpS... in which me3K corresponds to trimethyl-lysine 9 and pS to phosphoserine 10 of human histone H3
应用
Anti-trimethyl (Lys9)-phospho (Ser10)-Histone H3 Antibody is a rabbit monoclonal antibody for detection of trimethyl (Lys9)-phospho (Ser10)-Histone H3 also known as H3K9me3S10P, has been validated in WB, PIA, Mplex.
Research Category
Epigenetics & Nuclear Function
Epigenetics & Nuclear Function
Research Sub Category
Histones
Histones
目标描述
Mr 17kDa
外形
Protein A purified
0.2M Tris-glycine, pH 7.4, 0.15M NaCl, 100mM EDTA, 0.05% sodium azide, before the addition of glycerol to 30%
Format: Purified
储存及稳定性
Stable for 2 years at -20°C
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
WGK
WGK 1
Scott B Rothbart et al.
Molecular cell, 59(3), 502-511 (2015-07-28)
Access to high-quality antibodies is a necessity for the study of histones and their posttranslational modifications (PTMs). Here we debut the Histone Antibody Specificity Database (http://www.histoneantibodies.com), an online and expanding resource cataloging the behavior of widely used, commercially available histone
Meng Wang et al.
Cancer research, 74(10), 2825-2834 (2014-03-22)
Therapeutics that target the epidermal growth factor receptor (EGFR) can enhance the cytotoxic effects of ionizing radiation (IR). However, predictive genomic biomarkers of this radiosensitization have remained elusive. By screening 40 non-small cell lung cancer cell (NSCLC) lines, we established
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