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Merck
CN

05-799

Anti-Beta (β)-Amyloid antibody

UPSTATE®, mouse monoclonal, 11A5-B10

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关于此项目

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Clone:
11A5-B10, monoclonal
Species reactivity:
human, mouse
Application:
IHC, WB
Citations:
2
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产品名称

Anti-Amyloid β (Aβ)x-40 Antibody, clone 11A5-B10, ascites fluid, clone 11A5-B10, Upstate®

biological source

mouse

antibody form

ascites fluid

antibody product type

primary antibodies

clone

11A5-B10, monoclonal

species reactivity

human, mouse

manufacturer/tradename

Upstate®

technique(s)

immunohistochemistry: suitable, western blot: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

dry ice

Gene Information

human ... APP(351)

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General description

~4.5kDa

Immunogen

peptide corresponding to amino acids 34-40 of human Amyloid βx-40 peptide

Application

Detect Amyloid β (Aβ)x-40 using this Anti-Amyloid β (Aβ)x-40 Antibody, clone 11A5-B10 validated for use in WB, IH.

Biochem/physiol Actions

Amyloid βx-40 polypeptide

Analysis Note

routinely evaluated by immunoblot on of synthetic Amyloid βx-40 polypeptide

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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存储类别

12 - Non Combustible Liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable


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Céline Vrancx et al.
Molecular neurobiology, 58(12), 6647-6669 (2021-10-06)
The β-amyloid peptide (Aβ) is found as amyloid fibrils in senile plaques, a typical hallmark of Alzheimer's disease (AD). However, intermediate soluble oligomers of Aβ are now recognized as initiators of the pathogenic cascade leading to AD. Studies using recombinant
Yuta Takaichi et al.
Acta neuropathologica communications, 9(1), 10-10 (2021-01-09)
Alzheimer's disease (AD) is characterized by the accumulation of amyloid-β (Aβ) as senile plaques and cerebral amyloid angiopathy, and hyperphosphorylated tau (hp-tau) as neurofibrillary tangles in the brain. The AD-related pathology has been reported in several non-human animals, and most

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