产品名称
Anti-Amyloid β (Aβ)x-40 Antibody, clone 11A5-B10, ascites fluid, clone 11A5-B10, Upstate®
biological source
mouse
antibody form
ascites fluid
antibody product type
primary antibodies
clone
11A5-B10, monoclonal
species reactivity
human, mouse
manufacturer/tradename
Upstate®
technique(s)
immunohistochemistry: suitable, western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
dry ice
Gene Information
human ... APP(351)
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General description
~4.5kDa
Immunogen
peptide corresponding to amino acids 34-40 of human Amyloid βx-40 peptide
Application
Detect Amyloid β (Aβ)x-40 using this Anti-Amyloid β (Aβ)x-40 Antibody, clone 11A5-B10 validated for use in WB, IH.
Biochem/physiol Actions
Amyloid βx-40 polypeptide
Analysis Note
routinely evaluated by immunoblot on of synthetic Amyloid βx-40 polypeptide
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
12 - Non Combustible Liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
Céline Vrancx et al.
Molecular neurobiology, 58(12), 6647-6669 (2021-10-06)
The β-amyloid peptide (Aβ) is found as amyloid fibrils in senile plaques, a typical hallmark of Alzheimer's disease (AD). However, intermediate soluble oligomers of Aβ are now recognized as initiators of the pathogenic cascade leading to AD. Studies using recombinant
Yuta Takaichi et al.
Acta neuropathologica communications, 9(1), 10-10 (2021-01-09)
Alzheimer's disease (AD) is characterized by the accumulation of amyloid-β (Aβ) as senile plaques and cerebral amyloid angiopathy, and hyperphosphorylated tau (hp-tau) as neurofibrillary tangles in the brain. The AD-related pathology has been reported in several non-human animals, and most
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