推荐产品
生物来源
mouse
质量水平
抗体形式
purified antibody
抗体产品类型
primary antibodies
克隆
84, monoclonal
种属反应性
rat, mouse, human
制造商/商品名称
Upstate®
技术
immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
同位素/亚型
IgG
NCBI登记号
UniProt登记号
运输
dry ice
靶向翻译后修饰
unmodified
基因信息
human ... SH3KBP1(30011)
特异性
SETA
免疫原
6His and HA tagged fusion protein corresponding to full length rat SETA
应用
Detect SETA/CIN85/Ruk/SH3KBPI using this Anti-SETA/CIN85/Ruk/SH3KBPI Antibody, clone 84 validated for use in IP, WB & IC.
质量
routinely evaluated by immunoblot on RIPA lysates from NG108-15 cells
目标描述
85kDa
外形
Format: Purified
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
WGK
WGK 1
CIN85 associates with endosomal membrane and binds phosphatidic acid.
Jing Zhang, Xiudan Zheng, Xiao Yang, Kan Liao, Jing Zhang, Xiudan Zheng, Xiao Yang, Kan Liao
Cell research null
Susan Finniss et al.
Biochemical and biophysical research communications, 325(1), 174-182 (2004-11-04)
SETA/CIN85/Ruk is a multifunctional adaptor protein involved in signal transduction and attenuation downstream of receptor tyrosine kinases. It has a modular structure, and various isoforms that combine different protein-protein interaction domains have been proposed based on cDNA analysis. As a
B Chen et al.
The Journal of biological chemistry, 275(25), 19275-19281 (2000-06-20)
Expression of the src homology 3 (SH3) domain-containing expressed in tumorigenic astrocytes (SETA) gene is associated with the tumorigenic state in astrocytes. SETA encodes a variety of adapter proteins containing either one or two SH3 domains, as suggested by the
Tom Büchse et al.
Molecular & cellular proteomics : MCP, 10(10), M110-M110 (2011-07-05)
The Cbl-interacting 85-kDa protein (CIN85) plays an important role as a negative regulator of signaling pathways induced by receptor tyrosine kinases. By assembling multiprotein complexes this versatile adaptor enhances receptor tyrosine kinase-activated clathrin-mediated endocytosis and reduces phosphatidylinositol-3-kinase-induced phosphatidylinositol-3,4,5-trisphosphate production. Here
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