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生物来源
mouse
质量水平
抗体形式
purified immunoglobulin
抗体产品类型
primary antibodies
克隆
monoclonal
种属反应性
mouse, human
制造商/商品名称
Upstate®
技术
western blot: suitable
同位素/亚型
IgG
NCBI登记号
UniProt登记号
运输
wet ice
靶向翻译后修饰
unmodified
基因信息
human ... IKBKG(8517)
一般描述
IKKγ/IKK3 is also known as NEMO, FIP-3 and IKKAP-1
特异性
IKKγ/IKK3
免疫原
His-tagged, full-length human IKKgamma/IKK3
应用
Anti-IKKγ Antibody is an antibody against IKKγ for use in WB.
Research Category
Signaling
Signaling
Research Sub Category
Immunological Signaling
Immunological Signaling
质量
routinely evaluated by immunoblot on RIPA lysates from Jurkat cells
目标描述
48kDa
外形
Protein G Chromatography
Format: Purified
PBS, pH 7.4, containing 0.05% sodium azide
储存及稳定性
2 years at -20°C
分析说明
Control
Positive Antigen Control: Catalog #12-303, Jurkat cell lysate.
Positive Antigen Control: Catalog #12-303, Jurkat cell lysate.
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Sandeep Rana et al.
Chemical biology & drug design, 96(2), 773-784 (2020-04-03)
The release of an active drug from the prodrug generates a pro-fragment that typically has no biological activity and could result in adverse effects. By combining two drugs, wherein each drug acts as a pro-fragment of the other drug will
Masaaki Morikawa et al.
Microbiology (Reading, England), 152(Pt 9), 2801-2807 (2006-09-02)
The extracellular matrix produced by Bacillus subtilis B-1, an environmental strain that forms robust floating biofilms, was purified, and determined to be composed predominantly of gamma-polyglutamate (gamma-PGA), with a molecular mass of over 1,000 kDa. Both biofilm formation and gamma-PGA
Oncoprotein Suppression of Tumor Necrosis Factor-induced NF{kappa}B Activation Is Independent of Raf-controlled Pathways
Hanson, J. L., et al
The Journal of Biological Chemistry, 278, 34910-34917 (2003)
Deubiquitinase function of A20 maintains and repairs endothelial barrier after lung vascular injury.
Dheeraj Soni et al.
Cell death discovery, 4, 60-60 (2018-05-26)
Vascular endothelial cadherin (VE-cad) expression at endothelial adherens junctions (AJs) regulates vascular homeostasis. Here we show that endothelial A20 is required for VE-cad expression at AJs to maintain and repair the injured endothelial barrier. In endothelial cell (EC)-restricted Tnfaip3 (A20)
Maarten F de Jong et al.
Nature microbiology, 1(7), 16084-16084 (2016-08-31)
The linear ubiquitin chain assembly complex (LUBAC) is a multimeric E3 ligase that catalyses M1 or linear ubiquitination of activated immune receptor signalling complexes (RSCs). Mutations that disrupt linear ubiquitin assembly lead to complex disease pathologies including immunodeficiency and autoinflammation
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