推荐产品
生物来源
mouse
质量水平
抗体形式
purified immunoglobulin
抗体产品类型
primary antibodies
克隆
16C2, monoclonal
种属反应性
mouse, rat, human
制造商/商品名称
Upstate®
技术
flow cytometry: suitable
immunocytochemistry: suitable
western blot: suitable
同位素/亚型
IgG1κ
NCBI登记号
UniProt登记号
运输
wet ice
靶向翻译后修饰
phosphorylation (pSer239)
基因信息
human ... VASP(7408)
特异性
基于序列同源性，预计该抗体也会与犬和牛发生交叉反应。
磷酸化VASP
免疫原
磷酸化肽，对应于人磷酸化VASP（RKV[pS]KQE）的236-242位氨基酸
应用
研究子类别
细胞骨架信号转导
细胞骨架信号转导
研究类别
信号传导
信号传导
该抗磷酸化VASP (Ser239)抗体，克隆16C2经过验证可用在FC、WB、IC中，检测磷酸化VASP (Ser239)。
质量
通过免疫印迹对CTLL细胞的RIPA裂解液进行了常规评估
目标描述
50kDa
外形
100 µg来自无血清细胞培养上清液的小鼠IgG1，通过亲硫吸附和尺寸排阻色谱法纯化。 从1 ml PBS、0.1%叠氮化钠、PEG和蔗糖中冻干。 冻干粉末。用100 µL H2O复溶（15 min，RT），使最终浓度为1 mg/mL。 储存于 -20°C。
亲硫吸附色谱
形式：纯化
储存及稳定性
在-20°C下可保存2年
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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储存分类代码
10 - Combustible liquids
Olena Rudyk et al.
Circulation, 126(3), 287-295 (2012-06-12)
Although nitroglycerin has remained in clinical use since 1879, the mechanism by which it relaxes blood vessels to lower blood pressure remains incompletely understood. Nitroglycerin undergoes metabolism that generates several reaction products, including oxidants, and this bioactivation process is essential
Susan L Lindsay et al.
Journal of cell science, 120(Pt 17), 3011-3021 (2007-08-09)
The initial step in directed cell movement is lamellipodial protrusion, an action driven by actin polymerization. Enabled/vasodilator-stimulated phosphoprotein (Ena/VASP) family proteins are key regulators of this actin polymerization and can control lamellipodial protrusion rate. Ena/VASP proteins are substrates for modification
Jonel Trebicka et al.
Hepatology (Baltimore, Md.), 47(4), 1264-1276 (2008-03-06)
In cirrhosis, splanchnic vasodilation contributes to portal hypertension, subsequent renal sodium retention, and formation of ascites. Urotensin II(U-II) is a constrictor of large conductive vessels. Conversely, it relaxes mesenteric vessels, decreases glomerular filtration, and increases renal sodium retention. In patients
Beatrice B Yaroslavskiy et al.
Journal of cell science, 118(Pt 23), 5479-5487 (2005-11-18)
The osteoclast degrades bone in cycles; between cycles, the cell is motile. Resorption occurs by acid transport into an extracellular compartment defined by an alphavbeta3 integrin ring. NO has been implicated in the regulation of bone turnover due to stretch
Insulin stimulates glucose transport via nitric oxide/cyclic GMP pathway in human vascular smooth muscle cells.
Bergandi, L; Silvagno, F; Russo, I; Riganti, C; Anfossi, G; Aldieri, E; Ghigo, D; Trovati et al.
Arteriosclerosis, Thrombosis, and Vascular Biology null
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