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Merck
CN
所有图片(1)

文件

05-579

Sigma-Aldrich

Anti-Endostatin Antibody, clone 1837.46

clone 1837.46, Upstate®, from mouse

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UNSPSC代码:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物来源

mouse

质量水平

抗体形式

purified antibody

抗体产品类型

primary antibodies

克隆

1837.46, monoclonal

种属反应性

mouse, human

制造商/商品名称

Upstate®

技术

immunohistochemistry: suitable
western blot: suitable

同位素/亚型

IgG

NCBI登记号

UniProt登记号

运输

dry ice

靶向翻译后修饰

unmodified

基因信息

mouse ... Col18A1(12822)

特异性

endostatin

免疫原

Full-length recombinant murine endostatin

应用

Anti-Endostatin Antibody, clone 1837.46 is an antibody against Endostatin for use in WB, IH.
Research Category
Cell Structure
Research Sub Category
ECM Proteins

质量

routinely evaluated by immunoblot on 3T3 cell lysates

目标描述

Recognizes endostatin, Mr 22kDa An unidentified protein is also weakly detected at Mr 54kDa

外形

Thiophilic chromatography
50mM sodium phosphate, pH 8.0, 0.05% sodium azide, before the addition of glycerol to 30%
Format: Purified

储存及稳定性

2 years at -20°C

法律信息

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

WGK

WGK 1


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M C Cichy et al.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 42(12), 1150-1155 (2009-11-07)
Acute renal failure (ARF) is a frequent complication of Gram-negative sepsis, with a high risk of mortality. Lipopolysaccharide (LPS)-induced ARF is associated with hemodynamic changes that are strongly influenced by the overproduction of nitric oxide (NO) through the cytokine-mediated up-regulation
H M Strik et al.
Cancer, 91(5), 1013-1019 (2001-03-17)
Endostatin is a potent inhibitor of endothelial cell proliferation, angiogenesis, and tumor growth. Its occurrence and localization has not yet been examined in human brain tumors. The authors report the production of a monoclonal antibody and detection of endostatin in
B V Sauter et al.
Proceedings of the National Academy of Sciences of the United States of America, 97(9), 4802-4807 (2000-04-12)
Inhibition of angiogenesis has been shown to be an effective strategy in cancer therapy in mice. However, its widespread application has been hampered by difficulties in the large-scale production of the antiangiogenic proteins. This limitation may be resolved by in
Induction of the RNA regulator LIN28A is required for the growth and pathogenesis of RESTless breast tumors.
Gunsalus, KT; Wagoner, MP; Meyer, K; Potter, WB; Schoenike, B; Kim, S; Alexander et al.
Cancer Research null
M Dhanabal et al.
The Journal of biological chemistry, 274(17), 11721-11726 (1999-04-17)
Endostatin, a carboxyl-terminal fragment of collagen XVIII, has been shown to regress tumors in mice. In this study, we have analyzed the mechanism of endostatin action on endothelial cells and nonendothelial cells. Endostatin treatment of cow pulmonary artery endothelial cells

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