05-449
抗-Bin1 抗体，克隆99D
clone 99D, Upstate®, from mouse
别名:
Anti-AMPH2, Anti-AMPHL, Anti-CNM2, Anti-SH3P9
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
99D, monoclonal
Application:
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Species reactivity:
rat, human, mouse
Citations:
21
Technique(s):
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
immunoprecipitation (IP): suitable
western blot: suitable
Uniprot accession no.:
产品名称
抗-Bin1 抗体，克隆99D, clone 99D, Upstate®, from mouse
biological source
mouse
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
clone
99D, monoclonal
species reactivity
rat, human, mouse
manufacturer/tradename
Upstate®
technique(s)
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
isotype
IgG1κ
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... BIN1(274)
mouse ... Bin1(30948)
Analysis Note
通过免疫印迹对C2C12细胞的RIPA裂解液进行了常规评估
Application
抗-Bin1抗体（克隆99D）是用于IP、WB、 IH.的抗-Bin1 抗体。
研究子类别
BCL2 & 抑制
BCL2 & 抑制
研究类别
细胞凋亡 & 癌症
细胞凋亡 & 癌症
Biochem/physiol Actions
Bin1
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
56kDa
Immunogen
对应于人 Bin1氨基酸 189-398的部分融合蛋白 克隆99D
Other Notes
替代：MAB4131
由于许可协议限制，无法购买该产品进行转售。
Physical form
0.1M Tris-甘氨酸，pH 7.4，含0.05％叠氮化钠
形式：纯化
蛋白G色谱
Preparation Note
在-20°C下保存1年
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Suppression of MEK/ERK signalling by Myc: role of Bin-1.
Telfer, JF; Urquhart, J; Crouch, DH
Cellular Signalling null
Sisi Yang et al.
Neuron, 110(5), 824-840 (2022-01-24)
Autophagy is a cellular degradation pathway essential for neuronal health and function. Autophagosome biogenesis occurs at synapses, is locally regulated, and increases in response to neuronal activity. The mechanisms that couple autophagosome biogenesis to synaptic activity remain unknown. In this
R Wechsler-Reya et al.
Cancer research, 57(15), 3258-3263 (1997-08-01)
BIN1 is a putative tumor suppressor that was identified in a genetic screen for polypeptides that interact with the MYC oncoprotein. Using a set of six monoclonal antibodies, we identified and examined biochemical features and localization of cellular BIN1. Epitope
R J Wechsler-Reya et al.
Molecular and cellular biology, 18(1), 566-575 (1998-01-07)
Bin1 is a Myc-interacting protein with features of a tumor suppressor. The high level of Bin1 expression in skeletal muscle prompted us to investigate its role in muscle differentiation. Significant levels of Bin1 were observed in undifferentiated C2C12 myoblasts, a
Tiago Mendes et al.
Current protocols in cell biology, 86(1), e100-e100 (2019-12-27)
The proximity ligation assay (PLA) allows the detection and subcellular localization of protein-protein interactions with high specificity. We recently developed a high-content screening model based on primary hippocampal neurons cultured in 384-well plates and screened a library of ∼1100 compounds
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