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Merck
CN
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文件

05-446

Sigma-Aldrich

抗-p75NTR(神经营养因子受体)抗体,克隆ME20.4

clone A16/17, Upstate®, from mouse

别名:

p75 Low Affinity Neurotrophin Receptor, NGFR

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About This Item

UNSPSC代码:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物来源

mouse

质量水平

抗体形式

purified immunoglobulin

抗体产品类型

primary antibodies

克隆

A16/17, monoclonal

种属反应性

monkey, human

制造商/商品名称

Upstate®

技术

immunohistochemistry: suitable
immunoprecipitation (IP): suitable
neutralization: suitable
western blot: suitable

同位素/亚型

IgG1

NCBI登记号

UniProt登记号

运输

dry ice

靶向翻译后修饰

unmodified

基因信息

human ... NGFR(4804)

特异性

低亲和p75NTR

免疫原

人黑素瘤细胞系WM245。

应用

抗p75NTR(神经营养因子受体)抗体,克隆ME20.4可检测p75NTR(神经营养因子受体)的水平&已发表,&经验证可用于IP、WB、IH、NEUT。
研究子类别
激酶&磷酸酶

神经退行性疾病
研究类别
神经科学

质量

已通过免疫印迹法对HS294T细胞的RIPA裂解液进行了常规评估

目标描述

69kDa

联系

替代:04-1111

外形

0.1M Tris-甘氨酸(pH 7.4),0.15M NaCl,0.05%叠氮化钠,然后添加甘油至30%
形式:纯化
蛋白G层析

储存及稳定性

在-20°C下可保存2年

其他说明

由于许可协议限制,无法购买该产品进行转售。

法律信息

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

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WGK

WGK 1


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S M Mooney et al.
Neuroscience, 149(2), 372-381 (2007-09-18)
Organotypic cultures of rat cortex were used to test the hypotheses that nerve growth factor (NGF) is neuroprotective for immature cortical neurons and that ethanol abolishes this neuroprotection in a developmental stage-dependent manner. Samples were obtained on gestational day (G)
J Du et al.
The Journal of cell biology, 150(6), 1423-1434 (2000-09-20)
Brain-derived neurotrophic factor (BDNF) has been shown to regulate neuronal survival and synaptic plasticity in the central nervous system (CNS) in an activity-dependent manner, but the underlying mechanisms remain unclear. Here we report that the number of BDNF receptor TrkB
Low-affinity nerve growth factor receptor immunoreactivity in the human urinary bladder.
Wakabayashi, Y, et al.
Neuroscience Letters, 186, 9-12 (1995)
C Dominici et al.
Journal of neuro-oncology, 31(1-2), 57-64 (1997-01-01)
In neuroblastoma, high levels of mRNA for p140trkA and p75LNGFR neurotrophin receptors are predictive of favorable outcome. Their evaluation by Northern blot, however, requires substantial amounts of tissue and this prevents their routine evaluation as well as the possibility for
Immuno-electron microscopy characterization of human bone marrow stromal cells with anti-NGFR antibodies.
Caneva, L, et al.
Blood Cells, Molecules and Diseases, 21, 73-85 (1995)

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