05-368
抗-磷酸化-Ser/Thr-Pro，MPM-2抗体
clone MPM-2, Upstate®, from mouse
别名:
磷酸化丝氨酸/苏氨酸抗体
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
MPM-2, monoclonal
Species reactivity:
vertebrates
Application:
ELISA
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Technique(s):
ELISA: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
Citations:
254
产品名称
抗-磷酸化-Ser/Thr-Pro，MPM-2抗体, clone MPM-2, Upstate®, from mouse
biological source
mouse
antibody form
purified immunoglobulin
clone
MPM-2, monoclonal
species reactivity
vertebrates
manufacturer/tradename
Upstate®
technique(s)
ELISA: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
isotype
IgG1
shipped in
wet ice
target post-translational modification
phosphorylation (pSer/pThr)
Quality Level
相关类别
Analysis Note
对照
秋水仙胺处理的HeLa细胞裂解液或用3.7%多聚甲醛固定的A431有丝分裂细胞
秋水仙胺处理的HeLa细胞裂解液或用3.7%多聚甲醛固定的A431有丝分裂细胞
通过免疫印迹法对秋水仙胺处理的人HeLa癌细胞进行常规评估
Application
抗磷酸化Ser/Thr-Pro MPM-2抗体是一种用于检测磷酸化Ser/Thr-Pro（也称为有丝分裂蛋白#2）的小鼠单克隆抗体，&已在ELISA、IHC、IP & WB中进行了测试。
研究子类别
细胞周期，DNA 复制&修复
细胞周期，DNA 复制&修复
研究类别
表观遗传学&核功能
表观遗传学&核功能
Biochem/physiol Actions
在脯氨酸之后识别磷酸化丝氨酸或苏氨酸。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
该抗体可识别有丝分裂期间磷酸化的多种蛋白质。
根据您检测的蛋白质而变化
进入M（有丝分裂）期后，许多蛋白质会被M相促进因子（MPF）直接或间接磷酸化。MPM2单克隆抗体与M期真核细胞的50多种蛋白质上存在的含磷酸氨基酸的表位（含有LTPLK和FTPLQ结构域的肽）结合。
Immunogen
有丝分裂人HeLa细胞胞质裂解液
Other Notes
浓度：请参考批次特异性浓缩物的分析证书。
Physical form
形式：纯化
蛋白G纯化
蛋白G纯化的免疫球蛋白中的蛋白G纯化免疫球蛋白溶于30％甘油，0.07M Tris-甘氨酸（pH 7.4），0.105 M NaCl，0.035％叠氮化钠作为防腐剂的溶液中。
Preparation Note
自运送之日起在-20°C可稳定保存2年。避免反复冻融。为了最大程度地回收产品，在融化后和取下盖子之前，将原始样品瓶进行离心。
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
10 - Combustible liquids
wgk
WGK 1
J Cobb et al.
Developmental biology, 205(1), 49-64 (1999-01-12)
Little is known about the timing of meiotic prophase events during spermatogenesis in the mouse or how these events are related to cell-cycle progression. This work was designed to test hypotheses about the timing and biochemical correlates of developmental acquisition
Human papillomavirus type 16 E7 oncoprotein engages but does not abrogate the mitotic spindle assembly checkpoint.
Yu, Y; Munger, K
Virology null
S A Innocente et al.
Proceedings of the National Academy of Sciences of the United States of America, 96(5), 2147-2152 (1999-03-03)
The p53 tumor suppressor controls multiple cell cycle checkpoints regulating the mammalian response to DNA damage. To identify the mechanism by which p53 regulates G2, we have derived a human ovarian cell that undergoes p53-dependent G2 arrest at 32 degrees
Cyclin E controls Drosophila female germline stem cell maintenance independently of its role in proliferation by modulating responsiveness to niche signals.
Ables, ET; Drummond-Barbosa, D
Development null
Inhibitor-2 induced M-phase arrest in Xenopus cycling egg extracts is dependent on MAPK activation.
Arian Khandani,Mahmood Mohtashami,Anne Camirand
Cellular & Molecular Biology Letters null
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