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Merck
CN
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文件

安全信息

05-23-3801

Sigma-Aldrich

Endothelin 3, Human and Rat

Attenuates thrombin-evoked aggregation of human platelets.

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别名:
Endothelin 3, Human and Rat, ET-3, CTCFTYKDKECVYYCHLDIIW
经验公式(希尔记法):
C121H168N26O33S4
分子量:
2643.04
MDL编号:
UNSPSC代码:
12352202
NACRES:
NA.77

质量水平

检测方案

≥97% (HPLC)

形式

solid

制造商/商品名称

Calbiochem®

储存条件

OK to freeze
desiccated

溶解性

5% acetic acid: 0.5 mg/mL

运输

ambient

储存温度

−20°C

一般描述

Attenuates thrombin-evoked aggregation of human platelets. A potent stimulator of interleukin-6 production by endothelial cell lines. Reported to activate phopholipase C in fibroblasts expressing ETA receptors.
Attenuates thrombin-evoked aggregation of human platelets. A potent stimulator of interleukin-6 production by endothelial cell lines. Reported to activate phospholipase C in fibroblasts expressing ETA receptors.

生化/生理作用

Cell permeable: no
Primary Target
Stimulator of interleukin-6 production by endothelial cell lines
Product does not compete with ATP.
Reversible: no

包装

Yes

序列

H-Cys¹-Thr-Cys³-Phe-Thr-Tyr-Lys-Asp-Lys-Glu-Cys¹¹-Val-Tyr-Tyr-Cys¹⁵-His-Leu-Asp-Ile-Ile-Trp-OH (disulfide bonds: 1 → 15; 3 → 11)

外形

Supplied as a trifluoroacetate salt. Sold on the basis of peptide content.

制备说明

Dissolve peptide initially at 8 mg/ml in 80% cold acetic acid, then dilute with cold water to 5% acetic acid and 0.5 mg/ml peptide.

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.

其他说明

Gresser, O., et al. 1996. Biochem. Biophys. Res. Commun.224, 169.
Astarie-Dequeker, C., et al. 1995. Br. J. Pharmacol. 114, 524.
Xin, X., et al. 1995. Endocrinology 136, 132.
Brunner, F., et al. 1992. J. Mol. Cell. Cardiol.24, 1291.
Lamers, J.M., et al. 1992. Mol. Cell. Biochem. 116, 59.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

监管及禁止进口产品

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