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安全信息

05-23-2401

Sigma-Aldrich

Calcitonin, Salmon

Calcitonin, Salmon, CAS 47931-85-1, is a 32 amino acid synthetic calcitonin that is shown to stimulate bone formation and inhibit bone resorption. Has ability to cross mucous membranes.

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别名:
Calcitonin, Salmon
经验公式（希尔记法）:
C145H240N44O48S2
CAS号:
47931-85-1
分子量:
3431.85
MDL编号:
MFCD00133859
UNSPSC代码:
12352202
NACRES:
NA.77

质量水平

100

无菌性

non-sterile

检测方案

≥98% (HPLC)

形式

lyophilized

制造商/商品名称

Calbiochem®

储存条件

OK to freeze
desiccated (hygroscopic)

溶解性

5% acetic acid: 1 mg/mL

运输

ambient

储存温度

−20°C

InChI

1S/C145H240N44O48S2/c1-65(2)45-86(175-139(232)110(70(11)12)183-136(229)99-63-239-238-62-79(148)117(210)178-96(59-191)134(227)174-92(52-104(151)202)131(224)172-90(49-69(9)10)129(222)180-98(61-193)135(228)187-114(74(16)197)142(235)181-99)118(211)158-55-106(204)162-80(25-18-20-40-146)120(213)169-89(48-68(7)8)128(221)179-97(60-192)133(226)167-83(34-37-102(149)200)122(215)165-85(36-39-109(207)208)123(216)171-88(47-67(5)6)127(220)173-91(51-77-54-156-64-161-77)130(223)164-81(26-19-21-41-147)121(214)170-87(46-66(3)4)126(219)166-84(35-38-103(150)201)125(218)186-113(73(15)196)141(234)177-94(50-76-30-32-78(199)33-31-76)143(236)189-44-24-29-101(189)137(230)168-82(27-22-42-157-145(154)155)124(217)185-112(72(14)195)140(233)176-93(53-105(152)203)132(225)184-111(71(13)194)138(231)160-56-107(205)163-95(58-190)119(212)159-57-108(206)182-115(75(17)198)144(237)188-43-23-28-100(188)116(153)209/h30-33,54,64-75,79-101,110-115,190-199H,18-29,34-53,55-63,146-148H2,1-17H3,(H2,149,200)(H2,150,201)(H2,151,202)(H2,152,203)(H2,153,209)(H,156,161)(H,158,211)(H,159,212)(H,160,231)(H,162,204)(H,163,205)(H,164,223)(H,165,215)(H,166,219)(H,167,226)(H,168,230)(H,169,213)(H,170,214)(H,171,216)(H,172,224)(H,173,220)(H,174,227)(H,175,232)(H,176,233)(H,177,234)(H,178,210)(H,179,221)(H,180,222)(H,181,235)(H,182,206)(H,183,229)(H,184,225)(H,185,217)(H,186,218)(H,187,228)(H,207,208)(H4,154,155,157)

InChI key

BBBFJLBPOGFECG-UHFFFAOYSA-N

相关类别

一般描述

Synthetic, salmon calcitonin. A 32 amino acid residue peptide that is shown to stimulate bone formation and inhibit bone resorption. Has ability to cross mucous membranes. Has no significant effect on inositol phosphate accumulation.
Synthetic, salmon calcitonin. Calcitonin is a single-chain peptide hormone of 32 amino acid residues with a disulfide bridge between cysteines 1 and 7. It is produced in the parafollicular C cells of the thyroid gland and acts to stimulate bone formation by osteoblasts and inhibits bone resorption. Part of the effect of calcitonin appears to be mediated through increasing cAMP concentrations in osteoclasts. Has ability to cross mucus membranes. Has no significant effect on inositol phosphate accumulation.

包装

Yes

警告

Toxicity: Standard Handling (A)

序列

H-Cys¹-Ser-Asn-Leu-Ser-Thr-Cys⁷-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Gly-Thr-Pro-NH₂(disulfide bond: 1 → 7)

外形

Sold on the basis of peptide content.

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.

其他说明

Gennari, C. and Agnusdei, D. 1994. Br. J. Clin. Pract.48, 196.
Reginster, J.Y. 1993. Osteoporos. Int. 3 (Suppl. 2), S3.
MacIntyre, I. et al. 1988. Clin. Orthop.217, 45.
Chambers, T.J., et al. 1985. J. Pathol.145, 297.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

象形图

Skull and crossbones
GHS06

警示用语：

Danger

危险声明

H301

危险分类

Acute Tox. 3 Oral

WGK

WGK 3

法规信息

监管及禁止进口产品

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