生物来源
mouse
质量水平
抗体形式
purified antibody
抗体产品类型
primary antibodies
克隆
monoclonal
种属反应性
rat, mouse, bovine, human
制造商/商品名称
Upstate®
技术
immunoprecipitation (IP): suitable
同位素/亚型
IgG
NCBI登记号
UniProt登记号
运输
wet ice
靶向翻译后修饰
unmodified
基因信息
human ... PLCB1(23236)
特异性
PLCβ-1, also recognize the 100kDa and 41kDa fragments of PLCβ-1.1
免疫原
Mixed monoclonal antibodies raised against purified bovine PLCβ-1
应用
Detect PLCβ-1 using this Anti-PLCβ-1 Antibody validated for use in IP.
Research Category
Signaling
Signaling
Research Sub Category
Lipid Signaling
Lipid Signaling
质量
routinely evaluated by immunoprecipition of PLCβ-1 from a bovine brain membrane preparation, subsequent immunoblotting performed by the antibody
目标描述
150 kDa
外形
Protein G Chromatography
100mM Tris-glycine, pH 7.4, 0.15M NaCl with 0.05% sodium azide
Format: Purified
储存及稳定性
2 years at -20°C
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Three prime exonuclease I (TREX1) is Fos/AP-1 regulated by genotoxic stress and protects against ultraviolet light and benzo(a)pyrene-induced DNA damage.
Christmann, M; Tomicic, MT; Aasland, D; Berdelle, N; Kaina, B
Nucleic Acids Research null
P Sánchez-Blázquez et al.
The Journal of pharmacology and experimental therapeutics, 285(2), 820-827 (1998-05-15)
To analyze the selectivity of delta receptor subtypes to regulate different classes of G proteins, the expression of the alpha-subunits of Gi2, Gi3, Go1, Go2, Gq and G11 transducer proteins was reduced by administration of oligodeoxynucleotides (ODNs) complementary to sequences
Hideki Igarashi et al.
Developmental biology, 312(1), 321-330 (2007-10-27)
Inositol 1,4,5-trisphosphate generated by the action of a phospholipase C (PLC) mediates release of intracellular Ca2+ that is essential for sperm-induced activation of mammalian eggs. Much attention currently focuses on the role of sperm-derived PLCzeta in generating changes in egg
N Liu et al.
The Journal of biological chemistry, 271(1), 355-360 (1996-01-05)
To discover a new phospholipase C (PLC) related to cell growth, we screened a cDNA library prepared from regenerating rat liver. A novel PLC (PLC delta 4) encoding a polypeptide of 770 amino acids with structural similarity to PLC delta-type
Roberta Fiume et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 23(3), 957-966 (2008-11-26)
Inositide-specific phospholipase Cbeta1 (PLCbeta1) signaling in cell proliferation has been investigated thoroughly in the G(1) cell cycle phase. However, little is known about its involvement in G(2)/M progression. We used murine erythroleukemia cells to investigate the role of PLCbeta1 in
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