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生物来源
mouse
质量水平
抗体形式
purified immunoglobulin
抗体产品类型
primary antibodies
克隆
19B2, monoclonal
种属反应性
human, rat
制造商/商品名称
Upstate®
技术
immunoprecipitation (IP): suitable
western blot: suitable
同位素/亚型
IgG1
UniProt登记号
运输
wet ice
靶向翻译后修饰
unmodified
基因信息
human ... FGFR1(2260)
特异性
extra cellular domain for both (alpha and beta) human FGF receptor
免疫原
E. coli fusion protein corresponding to amino acids 23-325 of human FGF receptor beta (Flg)
应用
Anti-FGFR1 Antibody, clone 19B2 detects level of FGFR1 & has been published & validated for use in IP & WB.
Research Category
Signaling
Signaling
Research Sub Category
Growth Factors & Receptors
Growth Factors & Receptors
质量
routinely evaluated in sFGFR-1 (obtained from Alexis Biochemicals, Catalog # SFC-015)
目标描述
110 kDa
外形
Protein G Chromatography
0.1M Tris-glycine, pH 7.4, 0.15M NaCl containing 0.05% sodium azide
Format: Purified
储存及稳定性
2 years at -20°C or 2 months at 4°C
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
12 - Non Combustible Liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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Science (New York, N.Y.), 251(4994), 665-668 (1991-02-08)
Changes in heparin-binding fibroblast growth factor gene expression and receptor phenotype occur during liver regeneration and in hepatoma cells. The nucleotide sequence of complementary DNA predicts that three amino-terminal domain motifs, two juxtamembrane motifs, and two intracellular carboxyl-terminal domain motifs
Suppression of fibroblast growth factor receptor signaling inhibits pancreatic cancer growth in vitro and in vivo.
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Gastroenterology null
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The Journal of pharmacology and experimental therapeutics, 319(2), 515-522 (2006-07-27)
The beneficial effect exerted by angiotensin-converting enzyme inhibitors (ACEI) on vascular endothelium has been attributed to restoration of endothelial cell survival properties and improvement of angiogenesis. Fibroblast growth factor (FGF)-2 is an angiogenic factor for the microvascular endothelium, which tonically
Y Mazaki et al.
Molecular biology of the cell, 12(3), 645-662 (2001-03-17)
Paxillin acts as an adaptor protein in integrin signaling. We have shown that paxillin exists in a relatively large cytoplasmic pool, including perinuclear areas, in addition to focal complexes formed at the cell periphery and focal adhesions formed underneath the
Expression of a dominant negative FGF receptor inhibits axonal growth and FGF receptor phosphorylation stimulated by CAMs
Saffell, J. L., et al
Neuron, 18, 231-242 (1997)
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