05-1355
抗乙酰组蛋白H4 (Lys5/8/12/16) 抗体，克隆3HH4-4C10
ascites fluid, clone 3HH4-4C10, from mouse
别名:
H4KAc, Histone H4 (acetyl), H4 histone family, member N, H4 histone, family 2, histone 2, H4, histone 2, H4a, histone IV, family 2, histone cluster 2, H4a
产品名称
抗乙酰组蛋白H4 (Lys5/8/12/16) 抗体，克隆3HH4-4C10, ascites fluid, clone 3HH4-4C10, from mouse
biological source
mouse
antibody form
ascites fluid
antibody product type
primary antibodies
clone
3HH4-4C10, monoclonal
species reactivity
human
species reactivity (predicted by homology)
mouse (based on 100% sequence homology), rat (based on 100% sequence homology)
technique(s)
immunocytochemistry: suitable
western blot: suitable
isotype
IgG1κ
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
acetylation (Lys5/Lys8/Lys12/Lys16)
Quality Level
Gene Information
human ... H4C1(8359)
mouse ... H4C1(326619)
Analysis Note
对照
HeLa酸提取物裂解液
HeLa酸提取物裂解液
通过蛋白质印迹对HeLa酸提取物裂解液进行了评估。
蛋白质印迹分析：该抗体的1：2,000稀释液在10 µg HeLa酸提取物裂解液中检测到组蛋白H4。
蛋白质印迹分析：该抗体的1：2,000稀释液在10 µg HeLa酸提取物裂解液中检测到组蛋白H4。
Application
使用在WB，ICC中验证的抗乙酰化组蛋白H4（Lys5/8/12/16）抗体，克隆3HH4-4C10（小鼠单克隆抗体）检测乙酰化组蛋白H4（Lys5/8/12/16），也称为H4KAc，组蛋白H4（乙酰化）。
免疫细胞化学分析：
代表性批次的1：500稀释液在A431和HeLa细胞中检测到乙酰化组蛋白H4。
代表性批次的1：500稀释液在A431和HeLa细胞中检测到乙酰化组蛋白H4。
研究子类别
组蛋白
组蛋白
研究类别
表观遗传学&核功能
表观遗传学&核功能
Biochem/physiol Actions
该抗体可识别组蛋白H4。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
~13 kDa
组蛋白H4是参与真核细胞染色质结构的5种主要组蛋白之一。H4具有一个主要的球状结构域和一个长N末端的尾巴，其与核糖体核小体′串珠′结构体的结构有关。组蛋白H4的乙酰化发生在组蛋白尾部的几个不同的赖氨酸位置，并由称为组蛋白乙酰基转移酶（HATs）的酶家族完成。保守的核心组蛋白N末端尾部结构域的翻译后乙酰化通常与基因激活有关。
Immunogen
对应于在Lys5/8/12/16处乙酰化人组蛋白H4的线性肽。
表位：Lys5/8/12/16
Physical form
未纯化
纯化的小鼠单克隆IgG1κ 无防腐剂腹水腹水。
Preparation Note
自收到之日起在-20°C可稳定保存1年。
处理建议：收到后，在取下瓶盖之前，将小瓶离心并轻轻混合溶液。分装到微量离心管中，并储存于 -20°C。避免反复冻融循环，以免损坏 IgG 和影响产品性能。
处理建议：收到后，在取下瓶盖之前，将小瓶离心并轻轻混合溶液。分装到微量离心管中，并储存于 -20°C。避免反复冻融循环，以免损坏 IgG 和影响产品性能。
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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